Evidence map›Paper›PMID 38041832›Full record

ArticleThe Journal of international medical research2023

CT and

Milica Mitrovic-Jovanovic, Ognjan Skrobic, Strahinja Odalovic, Aleksandra Djikic Rom, Aleksandra Plavsic, Aleksandra Jankovic, Milena Kostadinovic, Nenad Ivanovic, Aleksandar Simic, Aleksandra Djuric-Stefanovic and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Milica Mitrovic-JovanovicDepartment of Digestive Radiology, Clinic for Digestive Surgery, University Clinical Centre of Serbia, No. 6 Dr. Koste Todorovica Street, Belgrade, Serbia.ORCID 0000-0002-7525-7615
Ognjan SkrobicDepartment of Esophageal and Gastric Surgery, Clinic for Digestive Surgery, University Clinical Centre of Serbia, No. 6 Koste Todorovica Street, Belgrade, Serbia.
Strahinja OdalovicDepartment of Radiology, Faculty of Medicine, University of Belgrade, No. 8 Dr. Subotica Street, Belgrade, Serbia.
Aleksandra Djikic RomDepartment of Pathology, Clinic for Digestive Surgery, University Clinical Centre of Serbia, No. 6 Dr. Koste Todorovica Street, Belgrade, Serbia.
Aleksandra PlavsicClinic of Allergy and Immunology, University Clinical Centre of Serbia, No. 2 Dr. Koste Todorovica Street, Belgrade, Serbia.
Aleksandra JankovicDepartment of Digestive Radiology, Clinic for Digestive Surgery, University Clinical Centre of Serbia, No. 6 Dr. Koste Todorovica Street, Belgrade, Serbia.
Milena KostadinovicCenter for Physical Medicine and Rehabilitation, University Clinical Centre of Serbia, No. 2 Pasterova Street, Belgrade, Serbia.
Nenad IvanovicDepartment of Esophageal and Gastric Surgery, Clinic for Digestive Surgery, University Clinical Centre of Serbia, No. 6 Koste Todorovica Street, Belgrade, Serbia.
Aleksandar SimicDepartment of Esophageal and Gastric Surgery, Clinic for Digestive Surgery, University Clinical Centre of Serbia, No. 6 Koste Todorovica Street, Belgrade, Serbia.
Aleksandra Djuric-StefanovicDepartment of Digestive Radiology, Clinic for Digestive Surgery, University Clinical Centre of Serbia, No. 6 Dr. Koste Todorovica Street, Belgrade, Serbia.
Jelena Djokic KovacDepartment of Digestive Radiology, Clinic for Digestive Surgery, University Clinical Centre of Serbia, No. 6 Dr. Koste Todorovica Street, Belgrade, Serbia.
University of Belgrade · RSUniverzitetski Klinički Centar Srbije · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic mediastinal fibrosis, also called sclerosing or fibrosing mediastinitis, is a very rare and aggressive fibroinflammatory process characterized by fibrous tissue proliferation in the mediastinal region. Herein, we present a rare case of idiopathic mediastinal fibrosis presenting with esophageal obstruction, most likely associated with immunoglobulin G (IgG4)-related disease, affecting the posterior mediastinum with intrapulmonary infiltration. Computed tomography revealed a narrowed lumen and thickened wall of the distal esophagus surrounded by a necrotic mass with infiltration into the nearby structures, suggesting a locally advanced malignant process. Positron emission tomography revealed intense accumulation of 18F-fluorodeoxyglucose, indicating an active inflammatory component, which complicates further differential diagnosis of mediastinal masses. Thoracoscopic biopsy and immunohistochemical analysis confirmed a fibroinflammatory process with perivascular lymphoid cell infiltration that was cluster of differentiation (CD)3 (++) and CD20 (++), with massive numbers of IgG4-immunoreactive plasma cells. Although a benign condition, sclerosing mediastinitis is a close mimicker of esophageal carcinoma, which cannot be differentiated by computed tomography or positron emission tomography and must be considered in a differential diagnosis.

Indexed as

CarcinomaFluorodeoxyglucose F18FibrosisHumansImmunoglobulin GMediastinitisPositron-Emission TomographyPositron Emission Tomography Computed TomographySclerosisTomography, X-Ray ComputedFluorodeoxyglucose F18Immunoglobulin Gcase reportcomputed tomographydifferential diagnosisesophageal carcinomaIdiopathic mediastinal fibrosisIgG4-related diseasepositron emission tomography

Identifiers

PMID38041832
PMCPMC10693803
OpenAlexW4389264436

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.