Evidence map›Paper›PMID 38041787›Full record

ArticleActa diabetologica2024

Aerobic exercise improves BK

Yujia Liu, Yue Cheng, Na Xiang, Zhiyuan Wang, Siyu Li, Lijing Gong, Xingqi Wang

Abstract read
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In one paragraph

Article in Acta diabetologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yujia LiuDepartment of Physical Education, Jiangsu Normal University, Xuzhou, China.ORCID http://orcid.org/0000-0001-6261-9827
Yue ChengDepartment of Physical Education, Jiangsu Normal University, Xuzhou, China.ORCID http://orcid.org/0000-0002-8588-6941
Na XiangCaoxian People's Hospital, Heze, China.
Zhiyuan WangChina Institute of Sport and Health Science, Beijing Sport University, Beijing, China.
Siyu LiChina Institute of Sport and Health Science, Beijing Sport University, Beijing, China.
Lijing GongChina Institute of Sport and Health Science, Beijing Sport University, Beijing, China.ORCID http://orcid.org/0000-0003-3502-0901
Xingqi WangBiomedical R&d Center, School of Life Science, Jiangsu Normal University, Tongshan District, No. 101, Shanghai Road, Xuzhou, Jiangsu, China. xingqi_wang_njuer@163.com.ORCID http://orcid.org/0000-0002-3421-8441
Beijing Sport University · CNJiangsu Normal University · CNCixian People's Hospital · CN

Funding

Foundation of Jiangxi Educational Commission 22KJB180017Natural Science Foundation of Xuzhou Municipality KC21029
6 · The paper itself

Abstract

aimsThis study aims to investigate the effect of aerobic exercise training on BK

methodsControl m/m mice and diabetic db/db mice were randomly assigned to sedentary groups (W and D) and exercise training groups (WE and DE). Mice in exercise groups underwent training sessions lasting for 12 weeks, with a speed of 12 m/min for 60 min, five times per week. The thoracic aorta was extracted isolated and examined for measurement of vascular structure, global levels of reactive oxygen species (ROS), vasodilation, and protein expression. Rat thoracic aorta vascular smooth muscle cells (USMCs) were cultured, and siRNA transfection was conducted to detect whether AMPK contributed to the regulation. ROS level and protein expression were measured.

resultsCompared with control mice, diabetic mice had a larger vascular medium thickness, impaired BK

conclusionsBK

Indexed as

Diabetes Mellitus, ExperimentalMuscle, Smooth, VascularAMP-Activated Protein KinasesAnimalsExerciseMiceNF-E2-Related Factor 2RatsReactive Oxygen SpeciesVasodilationAMP-Activated Protein KinasesNF-E2-Related Factor 2Reactive Oxygen SpeciesAerobic exerciseAMPK/Nrf2 pathwayBKCa channelDiabetes mellitusVascular smooth muscle

Identifiers

PMID38041787
OpenAlexW4389265895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.