Evidence map›Paper›PMID 38041514›Full record

ArticleBrain and behavior2023

The German version of the tablet-based UCSF Brain Health Assessment is sensitive to early symptoms of neurodegenerative disorders.

Toller Gianina, Stäger Lorena, Kumurasamy Dilaxy, Callahan Patrick, Köhn Florian, Münzer Thomas, Kunze Ursi, U Monsch Andreas, Possin Kate, Katherine P Rankin and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Enhancing early detection of cognitive impairment in primary care with the TabCAT-BHA.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Toller GianinaDepartment of Neurology, Kantonsspital St. Gallen, Gallen, Switzerland.ORCID 0000-0002-0200-7949
Stäger LorenaDepartment of Neurology, Kantonsspital St. Gallen, Gallen, Switzerland.
Kumurasamy DilaxyDepartment of Neurology, Kantonsspital St. Gallen, Gallen, Switzerland.
Callahan PatrickMemory and Aging Center, University of California San Francisco, San Francisco, California, USA.
Köhn FlorianGeriatrische Klinik St. Gallen, Gallen, Switzerland.
Münzer ThomasGeriatrische Klinik St. Gallen, Gallen, Switzerland.
Kunze UrsiMemory Clinic, University Department of Geriatric Medicine Felix Platter, Basel, Switzerland.
U Monsch AndreasMemory Clinic, University Department of Geriatric Medicine Felix Platter, Basel, Switzerland.
Possin KateMemory and Aging Center, University of California San Francisco, San Francisco, California, USA.
Katherine P RankinMemory and Aging Center, University of California San Francisco, San Francisco, California, USA.
Ansgar FelbeckerDepartment of Neurology, Kantonsspital St. Gallen, Gallen, Switzerland.
Kantonsspital St. Gallen · CHUniversity of California, San Francisco · USFelix Platter-Hospital · CHUniversity of St.Gallen · CH

Funding

Cantonal Hospital of St. Gallen This research work was financially supported by KSSG research grant (number 20/33
6 · The paper itself

Abstract

introductionCognition often remains unassessed in primary care. To improve early diagnosis of neurocognitive disorder (NCD) in Switzerland, the tablet-based UCSF brain health assessment (BHA) and brain health survey (BHS) were validated.

methodsThe German BHA, BHS, and Montreal Cognitive Assessment (MoCA) were administered to 67 patients with mild/major NCD and 50 controls. BHA includes subtests of memory, executive, visuospatial, and language functioning, and informant-based BHS asks about behavior and motor functioning.

resultsThe complete instrument (BHA + BHS) was most accurate at detecting mild NCD (AUC = 0.95) and NCD without amyloid pathology (AUC = 0.96), followed by the BHA. All measures were accurate (all AUCs > 0.95) at distinguishing major NCD and NCD with amyloid pathology (Alzheimer's disease [AD]) from controls. DISCUSSION: The German BHA and BHS are more sensitive to mild NCD and non-AD presentations than the MoCA and thus have a high potential to identify patients with NCD in primary care earlier than currently used screens.

Indexed as

Alzheimer DiseaseCognitive DysfunctionNeurodegenerative DiseasesBrainHumansMental Status and Dementia TestsNeurocognitive DisordersNeuropsychological Testscognitive screeningmajor neurocognitive disordermild neurocognitive disorderprimary caretablet-based testing

Identifiers

PMID38041514
PMCPMC10726871
OpenAlexW4389265248

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.