Evidence map›Paper›PMID 38041450›Full record

ArticleClinical transplantation2024

Association of body mass index with post-liver transplant outcomes.

Jessica M Ruck, Amy M Shui, Alexis A Jefferis, Andres Duarte Rojo, Robert S Rahimi, Daniel R Ganger, Elizabeth C Verna, Matthew Kappus, Daniela P Ladner, Dorry L Segev and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Temporal changes in obesity and outcomes for patients listed for liver transplant.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Jessica M RuckDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-5749-5505
Amy M ShuiDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Alexis A JefferisDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Andres Duarte RojoCenter for Liver Diseases, Thomas A. Starzl Transplantation Institute, Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Robert S RahimiAnnette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Baylor Scott and White Health, Dallas, Texas, USA.
Daniel R GangerDivision of Gastroenterology and Hepatology, Department of Medicine, Northwestern Medicine, Chicago, Illinois, USA.
Elizabeth C VernaCenter for Liver Disease and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.
Matthew KappusDivision of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Daniela P LadnerComprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Dorry L SegevDepartment of Surgery, New York University Grossman School of Medicine and Langone Health, New York, New York, USA.
Michael VolkDivision of Gastroenterology & Hepatology, and Transplantation Institute, Loma Linda University Health, Loma Linda, California, USA.
Amit TevarDepartment of Medicine, University of California San Francisco School of Medicine, San Francisco, California, USA.
Elizabeth A KingDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jennifer C LaiDepartment of Medicine, University of California San Francisco School of Medicine, San Francisco, California, USA.ORCID 0000-0003-2092-6380
Johns Hopkins University · USUniversity of California, San Francisco · USNorthwestern University · USBaylor University Medical Center · USColumbia University Irving Medical Center · USDuke University · USLoma Linda University Medical Center · USNew York University · USUniversity of Pittsburgh Medical Center · US

Funding

UCSF Liver Core CenterP30DK026743 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Holger Willenbring · 1986 to 2026
$30.7M
The spectrum of cognitive impairment including Alzheimer’s Disease and Related Dementias after liver transplantationR01AG059183 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer C. Lai · 2018 to 2026
$9.9M
The Impact of Frailty on Liver Transplant Outcomes in Older Adults with Hepatocellular CarcinomaK24AG080021 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer C. Lai · 2023 to 2026
$755k
Frailty and post-liver transplant delirium and cognitive impairment in older recipientsF32AG067642 · NIA · JOHNS HOPKINS UNIVERSITY · PI RUCK, JESSICA MOORE · 2021 to 2023
$258k
NIA NIH HHS F32 AG067642NIA NIH HHS K24 AG080021NIA NIH HHS R01 AG059183NIDDK NIH HHS P30 DK026743
6 · The paper itself

Abstract

backgroundPatients with obesity have inferior outcomes after general surgery procedures, but studies evaluating post-liver transplant (LT) outcomes have been limited by small sample sizes or lack of granularity of outcomes. We evaluated the relationship between obesity and post-LT outcomes, including those observed in other populations to be obesity-related.

methodsIncluded were 1357 LT recipients prospectively enrolled in the ambulatory pre-LT setting at 8 U.S. CENTERS: Recipient were categorized by body mass index (BMI, kg/m

resultsClasses 2-3 obesity was associated with higher adjusted odds than non-obesity of venous thrombosis [adjusted odds ratio (aOR) 2.06, 95% CI 1.01-4.23, p = .047] and wound dehiscence (aOR 2.45, 95% CI 1.19-5.06, p = .02). Compared with non-obese recipients, post-LT hospital stay was significantly longer for recipients with classes 2-3 obesity [p = .01; median (Q1-Q3) 9 (6-14) vs. 8 (6-12) days) or class 1 obesity [p = .002; 9 (6-14) vs. 8 (6-11) days].  Likelihood of ICU readmission, infection, discharge to a non-home facility, rejection, 30-day readmission, and 1-year readmission were similar across BMI categories (all p > .05).

conclusionCompared to non-obese recipients, obese recipients had similar post-LT survival but longer hospital stay and higher likelihood of wound dehiscence and venous thrombosis. These findings underscore that obesity alone should not preclude LT, but recipients with obesity should be monitored for obesity-related complications such as wound dehiscence and venous thrombosis.

Indexed as

Liver TransplantationVenous ThrombosisBody Mass IndexHumansObesityPostoperative ComplicationsRetrospective StudiesRisk FactorsTreatment OutcomeBMIliver transplantobesityoutcomes

Identifiers

PMID38041450
PMCPMC10918560
OpenAlexW4389274201

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.