Evidence map›Paper›PMID 38041165›Full record

ArticleGenome biology2023

TargetRNA3: predicting prokaryotic RNA regulatory targets with machine learning.

Brian Tjaden

Open access · goldAbstract read
In one paragraph

Article in Genome biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 22 citations in OpenAlex.

  1. Inducible Protein Knockdown via Engineered Small RNAs in Chlamydia.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Article
  3. Review
  4. Article
  5. Analysis of Human miRNA Derived From Bladder Epithelial Cells Infected With Uropathogenic Escherichia coli.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  6. Machine Learning Approaches for Predicting RNA-RNA/DNA Interactions.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  7. Article
  8. Article
  9. What makes a small RNA work?Nucleic acids research · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Identification of Small RNAs inInternational journal of molecular sciences · 2024
    Article
  18. Quantitative mapping of pseudouridines in bacteria RNA.bioRxiv : the preprint server for biology · 2024
    Article
  19. Article
  20. Strain ofPlants (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Brian TjadenDepartment of Computer Science, Wellesley College, Wellesley, MA, USA. btjaden@wellesley.edu.ORCID 0009-0002-8664-7296
Wellesley College · US

Funding

System and Methods for Analysis of Bacterial TranscriptomesR15GM102755 · NIGMS · WELLESLEY COLLEGE · PI TJADEN, BRIAN · 2013 to 2024
$1.5M
NIGMS NIH HHS GM102755NIGMS NIH HHS R15 GM102755
6 · The paper itself

Abstract

Small regulatory RNAs pervade prokaryotes, with the best-studied family of these non-coding genes corresponding to trans-acting regulators that bind via base pairing to their message targets. Given the increasing frequency with which these genes are being identified, it is important that methods for illuminating their regulatory targets keep pace. Using a machine learning approach, we investigate thousands of interactions between small RNAs and their targets, and we interrogate more than a hundred features indicative of these interactions. We present a new method, TargetRNA3, for predicting targets of small RNA regulators and show that it outperforms existing approaches. TargetRNA3 is available at https://cs.wellesley.edu/~btjaden/TargetRNA3 .

Indexed as

RNA, BacterialRNA, Small UntranslatedBase PairingGene Expression Regulation, BacterialMachine LearningRNA, MessengerRNA, BacterialRNA, MessengerRNA, Small UntranslatedProkaryotesRegulationsRNATarget prediction

Identifiers

PMID38041165
PMCPMC10691042
OpenAlexW4389225049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.