Observational studyBMC medicine2023
Coronary microvascular function in male physicians with burnout and job stress: an observational study.
Observational study in BMC medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The influence of workplace stressors on the risk of cardiovascular diseases among healthcare providers: a systematic review.Frontiers in psychiatry · 2025Pooled it
- Physician burnout and type D personality relate to pericoronary fat phenotype and role of sympathetic activation: a cross-sectional study.Scientific reports · 2026Article
- Burnout, resilience, and cardiometabolic phenotype in an academic medical faculty: an integrated cross-sectional assessment from the United Arab Emirates.Frontiers in endocrinology · 2026Article
- Effect of the Narcissism Subscale "Threatened Self" on the Occurrence of Burnout Among Male Physicians.Journal of clinical medicine · 2025Article
- Individual Work Attitudes and Work Ability.European journal of investigation in health, psychology and education · 2025Article
- Violence at work experienced by nursing professionals working in hospital units: an exploratory and correlational study.Revista latino-americana de enfermagem · 2025Article
- Early detection of occupational stress: Enhancing workplace safety with machine learning and large language models.PloS one · 2025Article
- Psychological interventions mitigated occupational stress in high-risk workers in Shenzhen, China.Frontiers in public health · 2025Article
- Work stress and burnout among radiology nurses: a cross-sectional study on the mediating role of effort-reward imbalance.Frontiers in public health · 2025Article
- Correction: Coronary microvascular function in male physicians with burnout and job stress: an observational study.BMC medicine · 2024Article
- The Psychoneuroimmunological Model of Moral Distress and Health in Healthcare Workers: Toward Individual and System-Level Solutions.Comprehensive psychoneuroendocrinology · 2024Review
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs a professional group, physicians are at increased risk of burnout and job stress, both of which are associated with an increased risk of coronary heart disease that is at least as high as that of other professionals. This study aimed to examine the association of burnout and job stress with coronary microvascular function, a predictor of major adverse cardiovascular events.
methodsThirty male physicians with clinical burnout and 30 controls without burnout were included. Burnout was assessed with the Maslach Burnout Inventory and job stress with the effort-reward imbalance and overcommitment questionnaire. All participants underwent myocardial perfusion positron emission tomography to quantify endothelium-dependent (cold pressor test) and endothelium-independent (adenosine challenge) coronary microvascular function. Burnout and job stress were regressed on coronary flow reserve (primary outcome) and two additional measures of coronary microvascular function in the same model while adjusting for age and body mass index.
resultsBurnout and job stress were significantly and independently associated with endothelium-dependent microvascular function. Burnout was positively associated with coronary flow reserve, myocardial blood flow response, and hyperemic myocardial blood flow (r partial = 0.28 to 0.35; p-value = 0.008 to 0.035). Effort-reward ratio (r partial = - 0.32 to - 0.38; p-value = 0.004 to 0.015) and overcommitment (r partial = - 0.30 to - 0.37; p-value = 0.005 to 0.022) showed inverse associations with these measures.
conclusionsIn male physicians, burnout and high job stress showed opposite associations with coronary microvascular endothelial function. Longitudinal studies are needed to show potential clinical implications and temporal relationships between work-related variables and coronary microvascular function. Future studies should include burnout and job stress for a more nuanced understanding of their potential role in cardiovascular health.
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