Evidence map›Paper›PMID 38041078›Full record

ArticleProteome science2023

Systematic proteomics profiling of lysine crotonylation of the lung at Pseudoglandular and Canalicular phases in human fetus.

Wei Wang, Wei Shi, Yinglan Wang, Yane Yang, Ping Li, Zhipeng Zeng, Wenlong Hu, Yumei Chen, Donge Tang, Yong Dai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proteome science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wei WangClinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology, ShenzhenPeople's Hospital, Shenzhen, Guangdong, 518020, People's Republic of China.
Wei ShiDepartment of Obstetrics and Gynecology, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern, University of Science and Technology, ShenzhenPeople's Hospital, Shenzhen, Guangdong, 518020, People's Republic of China.
Yinglan WangDepartment of Obstetrics and Gynecology, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern, University of Science and Technology, ShenzhenPeople's Hospital, Shenzhen, Guangdong, 518020, People's Republic of China.
Yane YangShenzhen Far East Women & Children Hospital, Shenzhen, 518000, Guangdong, China.
Ping LiShenzhen Far East Women & Children Hospital, Shenzhen, 518000, Guangdong, China.
Zhipeng ZengClinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology, ShenzhenPeople's Hospital, Shenzhen, Guangdong, 518020, People's Republic of China.
Wenlong HuClinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology, ShenzhenPeople's Hospital, Shenzhen, Guangdong, 518020, People's Republic of China.
Yumei ChenClinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology, ShenzhenPeople's Hospital, Shenzhen, Guangdong, 518020, People's Republic of China.
Donge TangClinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology, ShenzhenPeople's Hospital, Shenzhen, Guangdong, 518020, People's Republic of China. donge66@126.com.
Yong DaiClinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology, ShenzhenPeople's Hospital, Shenzhen, Guangdong, 518020, People's Republic of China. daiyong22@aliyun.com.
Southern University of Science and Technology · CNJinan University · CN

Funding

Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Science and Technology Planning Project of Guangdong Province, China 2017B020209001Sanming project of medicine in Shenzhen SZSM201812078
6 · The paper itself

Abstract

Lung tissue is an important organ of the fetus, and genomic research on its development has improved our understanding of the biology of this tissue. However, the proteomic research of developing fetal lung tissue is still very scarce. We conducted comprehensive analysis of two developmental stages of fetal lung tissue of proteomics. It showed the developmental characteristics of lung tissue, such as the down-regulation of metabolism-related protein expression, the up-regulation of cell cycle-related proteins, and the regulation in proteins and pathways related to lung development. In addition, we also discovered some key core proteins related to lung development, and provided some key crotonylation modification sites that regulation during lung tissue development. Our comprehensive analysis of lung proteomics can provide a more comprehensive understanding of the developmental status of lung tissue, and provide a certain reference for future research and epigenetics of lung tissue.

Indexed as

BioinformaticsEpigeneticsLung developmentLysine crotonylationProteomics

Identifiers

PMID38041078
PMCPMC10691156
OpenAlexW4389224622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.