Evidence map›Paper›PMID 38041064›Full record

ArticleBMC oral health2023

Formulation and antibacterial properties of lollipops containing of chitosan- zinc oxide nano particles on planktonic and biofilm forms of Streptococcus mutans and Lactobacillus acidophilus.

Hamideh Sadat Mohammadipour, Parastoo Tajzadeh, Mahshid Atashparvar, Samira Yeganehzad, Maryam Erfani, Fatemeh Akbarzadeh, Sima Gholami

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hamideh Sadat MohammadipourRestorative and Cosmetic Dentistry, Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Parastoo TajzadehKashmar School of Medical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahshid AtashparvarMashhad University of Medical Sciences, Mashhad, Iran.
Samira YeganehzadDepartment of Food Processing, Research Institute of Food Science and Technology (RIFST), Mashhad, Iran.
Maryam ErfaniRadiology Department, Razavi International Hospital, Mashhad, Iran.
Fatemeh AkbarzadehDepartment of Chemistry, Faculty of Basic Sciences, Islamic Azad University, Mashhad, Iran.
Sima GholamiDepartment of Restorative and Cosmetic Dentistry, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran. GholamiS991@mums.ac.ir.
Mashhad University of Medical Sciences · IRImam Reza International University · IRIslamic Azad University, Mashhad · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to formulate and characterize the experimental lollipops containing chitosan- zinc oxide nanoparticles (CH-ZnO NPs) and investigate their antimicrobial effects against some cariogenic bacteria. The CH-ZnO NPs were synthesized and characterized by X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR) analysis, and Transmission electron microscope (TEM). Then, four groups were made, including lollipops coated with 2 and 4 ml of CH-ZnO NPs, 0.7 ml CH-ZnO NPs incorporated lollipops, and those with no CH-ZnO NPs. Their antibacterial effectiveness against Streptococcus mutans and Lactobacillus acidophilus was evaluated by direct contact test and tissue culture plate method in planktonic and biofilm phases, respectively. Chlorhexidine mouthrinse (CHX) was used as a positive control group. In the planktonic phase, the antibacterial properties of both groups coated with CH-ZnO NPs were comparable and significantly higher than incorporated ones. There was no significant difference between CHX and the lollipops coated with 4 ml of NPs against S. mutans and CHX and two coated groups against L. acidophilus. None of the experimental lollipops in the biofilm phase could reduce both bacteria counts. The experimental lollipops coated with 2 and 4 ml of CH-ZnO NPs could reveal favorable antimicrobial properties against two cariogenic bacteria in the planktonic phase.

Indexed as

Anti-Infective AgentsChitosanZinc OxideAnti-Bacterial AgentsBiofilmsHumansLactobacillus acidophilusMicrobial Sensitivity TestsStreptococcus mutansAnti-Bacterial AgentsAnti-Infective AgentsChitosanZinc OxideAnti-caries lollipopChlorhexidineDental cariesLactobacillus acidophilusNano chitosanStreptococcus mutansZinc oxide

Identifiers

PMID38041064
PMCPMC10693077
OpenAlexW4389248631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.