Evidence map›Paper›PMID 38041061›Full record

ArticleBMC public health2023

HIV assisted partner services (aPS) to support integrated HIV and hypertension screening in Kenya: a pre-post intervention study.

Beatrice Wamuti, Betsy Sambai, Christine Magambo, Margaret Ndegwa, Paul Macharia, Tecla M Temu, Carey Farquhar, David Bukusi

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Beatrice WamutiHarvard T. H. Chan School of Public Health, Harvard University, 677 Huntington Avenue, Boston, MA, 02115, USA. beatrice_wamuti@hsph.harvard.edu.
Betsy SambaiUniversity of Washington - Kenya, Nairobi, Kenya.
Christine MagamboVoluntary Counselling and Testing (VCT) and HIV Prevention Unit, Kenyatta National Hospital, Nairobi, Kenya.
Margaret NdegwaUniversity of Washington - Kenya, Nairobi, Kenya.
Paul MachariaResearch and Programs Department, Kenyatta National Hospital, Nairobi, Kenya.
Tecla M TemuDepartment of Global Health, University of Washington, Seattle, USA.
Carey FarquharDepartment of Global Health, University of Washington, Seattle, USA.
David BukusiVoluntary Counselling and Testing (VCT) and HIV Prevention Unit, Kenyatta National Hospital, Nairobi, Kenya.
Kenyatta National Hospital · KEUniversity of Washington · USHarvard University · USUniversity of Nairobi · KE

Funding

Promoting Diversity, Equity, and Inclusivity in Research Training to Optimize HIV Prevention and TreatmentD43TW009580 · FIC · UNIVERSITY OF WASHINGTON · PI CAREY FARQUHAR, John Kinuthia · 2013 to 2026
$4.8M
Women and HIV: Translation of Research into Practice-WLHIV Post-Graduate Research FellowshipD43TW009783 · FIC · UNIVERSITY OF WASHINGTON · PI Elizabeth Anne BUKUSI, CAREY FARQUHAR · 2015 to 2026
$4.1M
Global Infectious Diseases and HPV Research Training in KenyaD43TW010905 · FIC · AGA KHAN UNIVERSITY (KENYA) · PI CHUNG, MICHAEL HOONBAE, TEMMERMAN, MARLEEN · 2018 to 2023
$1.2M
FIC NIH HHS D43 TW009580FIC NIH HHS D43 TW009783FIC NIH HHS D43 TW010905
6 · The paper itself

Abstract

backgroundPeople living with HIV (PLWH) have a higher risk of developing hypertension compared to HIV uninfected individuals. HIV assisted partner services (aPS), where PLWH are assisted by a healthcare provider to disclose their status to sexual and / or drug injecting partner(s), offers an opportunity for integrated HIV and hypertension screening. We evaluated the feasibility of the aPS model in supporting integrated HIV and hypertension screening at the Kenyatta National Hospital, Kenya.

methodsBetween August 2019 and December 2020, we conducted a pre-post intervention study. We enrolled women receiving HIV testing services (HTS) with confirmed hypertension (female index clients) and traced their male relatives for HIV and hypertension screening and reviewed management at 3-months. Hypertension was defined as systolic blood pressure (SBP) ≥ 140 mmHg, diastolic blood pressure (DBP) ≥ 90 mmHg, and/or use of antihypertensive medication.

resultsOne hundred female index clients (median age: 55 years; interquartile range (IQR): 47-65) mentioned 165 male relatives (median: 49 years; IQR: 40-59) of whom 35% (n = 58/165) were enrolled. Of the male relatives, 29% had hypertension (n = 17/58), 34% had pre-hypertension (n = 20/58), and none were HIV-positive (n = 0/58). Among the female index clients, there was a statistically significant decline in SBP (pre: 156 mmHg, post: 133 mmHg, p-value: < 0.0001) and DBP (pre: 97 mmHg, post: 80 mmHg, p-value: < 0.0001), and increase in antihypertensive medication uptake (pre: 91%, n = 84/92; post: 98%, n = 90/92; X

conclusionHIV aPS holds promise for integrated HIV and hypertension screening among at-risk clients and their families. Twenty-nine percent of the male relatives had hypertension, higher than the national prevalence (24%), while one-third had pre-hypertension. We observed relatively high participant retention, reductions in blood pressure, and increase in antihypertensive medication uptake among those with confirmed hypertension. Future research expanding the aPS model to other non-communicable diseases through larger studies with longer follow-ups is required to better assess causal relationships and optimize integrated service delivery.

Indexed as

Delivery of Health Care, IntegratedHIV InfectionsHypertensionPrehypertensionAntihypertensive AgentsBlood PressureFemaleHumansKenyaMaleMass ScreeningMiddle AgedAntihypertensive AgentsAssisted partner servicesHIVHypertensionIntegration

Identifiers

PMID38041061
PMCPMC10693028
OpenAlexW4389224473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.