Evidence map›Paper›PMID 38041050›Full record

ArticleBMC oral health2023

Modeling longitudinal oral health status and pneumonia risk: secondary data analyses of an integrated dental-medical cohort.

Richard L Berg, Ingrid Glurich, Aloksagar Panny, Frank A Scannapieco, Jeffrey Miecznikowski, Jeffrey VanWormer, Amit Acharya

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Richard L BergOffice of Research Computing and Analytics, Marshfield Clinic Research Institute, Marshfield, WI, USA.
Ingrid GlurichCancer Care and Research Center, Marshfield Clinic Research Institute, Marshfield, WI, USA. Glurich.Ingrid@marshfieldresearch.org.
Aloksagar PannyClinical Informatics, Methodist Health System, Dallas, TX, USA.
Frank A ScannapiecoDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, Foster Hall, Buffalo, NY, USA.
Jeffrey MiecznikowskiDepartment of Biostatistics School of Public Health and Health Professions, University at Buffalo, Kimball Tower, Buffalo, NY, USA.
Jeffrey VanWormerCenter for Clinical Epidemiology & Population Health, Marshfield Clinic Research Institute, Marshfield, WI, USA.
Amit AcharyaAdvocate Aurora Health, 3075 Highland Parkway, Suite 600, Downers Grove, IL, 60515, USA. Amit.Acharya@aah.org.
University at Buffalo, State University of New York · USAdvocate Health Care · USMarshfield Clinic · USMarshfield Clinic · USMethodist Dallas Medical Center · USStatistical Research (United States) · US

Funding

Secondary Analysis of EHR Data to Examine Relative Impact of Oral Health History on Incident Pneumonia by SettingsR03DE027020 · NIDCR · MARSHFIELD CLINIC RESEARCH FOUNDATION · PI ACHARYA, AMIT · 2018 to 2019
$335k
NIDCR NIH HHS 1R03DE027020-01A1NIDCR NIH HHS R03 DE027020
6 · The paper itself

Abstract

backgroundMounting evidence indicates potential associations between poor oral health status (OHS) and increased pneumonia risk. Relative pneumonia risk was assessed in the context of longitudinally documented OHS.

methodsElectronic medical/dental patient data captured from 2007 through 2019 were retrieved from the integrated health records of Marshfield Clinic Health Systems. Participant eligibility initiated with an assessment of OHS, stratified into the best, moderate, or worst OHS groups, with the additional criterion of 'no pneumonia diagnosis in the past 90 days'. Pneumonia incidence was longitudinally monitored for up to 1 year from each qualifying dental visit. Models were assessed, with and without adjustment for prior pneumonia incidence, adjusted for smoking and subjected to confounding mitigation attributable to known pneumonia risk factors by applying propensity score analysis. Time-to-event analysis and proportional hazard modeling were applied to investigate relative pneumonia risk over time among the OHS groups.

resultsModeling identified associations between any incident pneumonia subtype and 'number of missing teeth' (p < 0.001) and 'clinically assessed periodontal status' (p < 0.01), which remained significant following adjustment for prior pneumonia incidence and smoking. The hazard ratio (HR) for 'any incident pneumonia' in the best OHS group for 'number of missing teeth' was 0.65, 95% confidence interval (CI) [0.54 - 0.79] (unadjusted) and 0.744, 95% CI [0.61 - 0.91] (adjusted). The HR for 'any incident pneumonia' in the best 'clinically assessed periodontal status' group was 0.72, 95% CI [0.58 - 0.90] (unadjusted) and 0.78, 95% CI [0.62 - 0.97] (adjusted). CONCLUSION/CLINICAL RELEVANCE: Poor OHS increased pneumonia risk. Proactive attention of medical providers to patient OHS and health literacy surrounding oral-systemic disease association is vital, especially in high-risk populations.

Indexed as

Oral HealthPneumoniaHumansRisk FactorsSecondary Data AnalysisOral healthPneumoniaProbabilistic modelsPropensity scoreRisk assessment

Identifiers

PMID38041050
PMCPMC10690969
OpenAlexW4389236716

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.