Evidence map›Paper›PMID 38040943›Full record

ArticleAnalytical and bioanalytical chemistry2024

Potential of measured relative shifts in collision cross section values for biotransformation studies.

Christian Lanshoeft, Raphael Schütz, Frédéric Lozac'h, Götz Schlotterbeck, Markus Walles

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Christian LanshoeftBiomedical Research, PK Sciences, Novartis Pharma AG, Fabrikstrasse 14 (Novartis Campus), 4056, Basel, Switzerland. christian.lanshoeft@novartis.com.ORCID http://orcid.org/0000-0002-2405-0227
Raphael SchützSchool of Life Sciences FHNW, Institute for Chemistry and Bioanalytics, University of Applied Sciences and Arts Northwestern Switzerland, Hofackerstrasse 30, 4132, Muttenz, Switzerland.ORCID http://orcid.org/0009-0000-6945-9299
Frédéric Lozac'hBiomedical Research, PK Sciences, Novartis Pharma AG, Fabrikstrasse 14 (Novartis Campus), 4056, Basel, Switzerland.ORCID http://orcid.org/0000-0003-4911-2807
Götz SchlotterbeckSchool of Life Sciences FHNW, Institute for Chemistry and Bioanalytics, University of Applied Sciences and Arts Northwestern Switzerland, Hofackerstrasse 30, 4132, Muttenz, Switzerland.ORCID http://orcid.org/0000-0002-9082-2846
Markus WallesBiomedical Research, PK Sciences, Novartis Pharma AG, Fabrikstrasse 14 (Novartis Campus), 4056, Basel, Switzerland.ORCID http://orcid.org/0000-0001-8376-8311
Novartis (Switzerland) · CHFHNW University of Applied Sciences and Arts · CHUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ion mobility spectrometry-mass spectrometry (IMS-MS) separates gas phase ions due to differences in drift time from which reproducible and analyte-specific collision cross section (CCS) values can be derived. Internally conducted in vitro and in vivo metabolism (biotransformation) studies indicated repetitive shifts in measured CCS values (CCS

Indexed as

CysteamineNitrogenBiotransformationMass SpectrometryCysteamineNitrogenBiotransformation assignmentCCSonDemandCollision cross sectionIon mobility spectrometry mass spectrometryMetabolite mapping

Identifiers

PMID38040943
PMCPMC10761390
OpenAlexW4389273262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.