ArticleVision research2024
Mapping the daily rhythmic transcriptome in the diabetic retina.
Ryan P Silk, Hanagh R Winter, Ouria Dkhissi-Benyahya, Carmella Evans-Molina, Alan W Stitt, Vijay K Tiwari, David A Simpson, Eleni Beli
Open access · hybridAbstract read
In one paragraphArticle in Vision research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors at 3 institutions in 5 countries.
Ryan P SilkWellcome Wolfson Institute for Experimental Medicine, Queens' University Belfast, Northern Ireland, United Kingdom.
Hanagh R WinterWellcome Wolfson Institute for Experimental Medicine, Queens' University Belfast, Northern Ireland, United Kingdom.
Ouria Dkhissi-BenyahyaUniv. Lyon, Université Lyon 1, Inserm, Stem Cell and Brain Research Institute U1208, 69500 Bron, France.
Carmella Evans-MolinaCenter for Diabetes and Metabolic Disease, Indiana University School of Medicine, Indianapolis, IN, USA.
Alan W StittWellcome Wolfson Institute for Experimental Medicine, Queens' University Belfast, Northern Ireland, United Kingdom.
Vijay K TiwariWellcome Wolfson Institute for Experimental Medicine, Queens' University Belfast, Northern Ireland, United Kingdom; Institute of Molecular Medicine, University of Southern Denmark, Odense C, Denmark; Danish Institute for Advanced Study (DIAS), Odense M, Denmark; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.
David A SimpsonWellcome Wolfson Institute for Experimental Medicine, Queens' University Belfast, Northern Ireland, United Kingdom.
Eleni BeliWellcome Wolfson Institute for Experimental Medicine, Queens' University Belfast, Northern Ireland, United Kingdom. Electronic address: e.beli@qub.ac.uk.
Queen's University Belfast · GBIndiana University School of MedicineUniversité Claude Bernard Lyon 1 · FR
Funding
The Integrated Stress Response in Human Islets During Early T1DU01DK127786 · NIDDK · UNIVERSITY OF CHICAGO · PI EVANS-MOLINA, CARMELLA, MIRMIRA, RAGHAVENDRA G · 2020 to 2025
$7.1MMechanisms of Beta Cell Function in Health and DiseaseR01DK093954 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EVANS-MOLINA, CARMELLA · 2011 to 2019
$3.5MBiomarkers Of Beta Cell Stress In Type 1 Diabetes (BetaMarker)UC4DK104166 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EIZIRIK, DECIO LAKS, EVANS-MOLINA, CARMELLA · 2014 to 2014
$2.4MControl of beta cell function and survival by RYR2-mediated calcium signalsR01DK127236 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EVANS-MOLINA, CARMELLA · 2021 to 2025
$2.2Mβ cell miRNAs Function as Molecular Hubs of Type 1 Diabetes PathogenesisR01DK127308 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EVANS-MOLINA, CARMELLA · 2021 to 2024
$1.7MRegulation of Calcium Homeostasis in the Pancreatic Beta CellI01BX001733 · VA · RLR VA MEDICAL CENTER · PI Carmella Evans-Molina · 2013 to 2026
–BLRD VA I01 BX001733NIDDK NIH HHS R01 DK093954NIDDK NIH HHS R01 DK127236NIDDK NIH HHS R01 DK127308NIDDK NIH HHS U01 DK127786NIDDK NIH HHS UC4 DK104166NIH, R01 DK093954, R01 DK127308, U01DK127786, UC4 DK 104166, JDRF
6 · The paper itselfAbstract
Retinal function changes dramatically from day to night, yet clinical diagnosis, treatments, and experimental sampling occur during the day. To begin to address this gap in our understanding of disease pathobiology, this study investigates whether diabetes affects the retina's daily rhythm of gene expression. Diabetic, Ins2
Indexed as
Diabetes MellitusDiabetic RetinopathyAnimalsCircadian RhythmMicePhotoperiodRetinaTranscriptome
Identifiers
PMID38039846
PMCPMC11330665
OpenAlexW4389158419
What OpenQuestion holds
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LicenceCC BY
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