Evidence map›Paper›PMID 38039494›Full record

ReviewJornal brasileiro de nefrologia

Trimethylamine N-oxide and kidney diseases: what do we know?

Ozkan Gungor, Nuri Baris Hasbal, Demet Alaygut

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. The gut-heart axis in cardio-oncology.Cardiovascular research · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Serum Trimethylamine N-Oxide Levels as a Predictor of Peripheral Arterial Disease in Kidney Transplant Recipients.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Ozkan GungorKahramanmaras Sutcu Imam University, School of Medicine, Department of Internal Medicine, Kahramanmaras, Turkey.
Nuri Baris HasbalKoc University, School of Medicine, Department of Internal Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-2229-5140
Demet AlaygutIzmir Katip Celebi University, School of Medicine, Department of Pediatrics, Izmir, Turkey.
Izmir Kâtip Çelebi University · TRKahramanmaraş Sütçü İmam University · TRKoç University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the human gut, there is a metabolically active microbiome whose metabolic products reach various organs and are used in the physiological activities of the body. When dysbiosis of intestinal microbial homeostasis occurs, pathogenic metabolites may increase and one of them is trimethyl amine-N-oxide (TMAO). TMAO is thought to have a role in the pathogenesis of insulin resistance, diabetes, hyperlipidemia, atherosclerotic heart diseases, and cerebrovascular events. TMAO level is also associated with renal inflammation, fibrosis, acute kidney injury, diabetic kidney disease, and chronic kidney disease. In this review, the effect of TMAO on various kidney diseases is discussed.

Indexed as

Acute Kidney InjuryDiabetic NephropathiesNephritisHumansMethylaminesMethylaminestrimethyloxamine

Identifiers

PMID38039494
PMCPMC10962421
OpenAlexW4389222917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.