Evidence map›Paper›PMID 38039183›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2024

Effect of examining lymph nodes count on mortality risk in resected T1 non-small-cell lung cancer.

Jun Zeng, Qi Liu, Ruiming Chang, Yufan Chen, Zhongjie Yu, Bin Yi, Yang Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Spirited discussion: lymph node count versus nodal station count.Interdisciplinary cardiovascular and thoracic surgery · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jun ZengDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Qi LiuDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Ruiming ChangDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Yufan ChenDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Zhongjie YuDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Bin YiDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Yang GaoDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0003-4834-7997

Funding

National Clinical Research Center for Geriatric Disorders 2021LNJJ17National Multidisciplinary Cooperative Diagnosis and Treatment Capacity Building Project for Major Diseases z027002Natural Science Foundation of Hunan Province 2022JJ30925
6 · The paper itself

Abstract

objectivesThis study aims to estimate the effect of the examined lymph node count (ELNC) on the cancer-related mortality risk and non-cancer-related mortality risk in patients with resected T1 non-small-cell lung cancer (NSCLC).

methodsPatients diagnosed as primary T1 NSCLC between 2000 and 2017 were extracted from the Surveillance, Epidemiology and End Results database. Patients were divided into 2 groups according to the ELNC cutoff value, which was calculated based on overall survival outcomes. Propensity score matching was used to equalize the differences in baseline characteristics between groups.

resultsA total of 38 242 resected T1 NSCLC patients were extracted from the database with the ELNC cutoff value of 8. After propensity score matching, 27 676 patients were included in this study. Examining ≥8 ELNC was associated with a more accurate assessment of lymph node (LN) metastasis and significantly improving the prognosis. These trends remained consistent in subgroup analysis by histology type. In competing risk mode, examining ≥8 LNs could significantly reduce the risk of death from lung cancer, risk of death from chronic obstructive pulmonary disease, and risk of death from cardiac diseases. In the subgroup analysis, these trends were consistent.

conclusionsGiven the mortality risk associated with lung cancer, chronic obstructive pulmonary disease, and cardiac diseases, at least 8 LNs should be examined in surgery for T1 NSCLC.

Indexed as

Cancer-related mortality riskCardiac diseasesChronic obstructive pulmonary diseaseExamined lymph nodesNon-small-cell lung cancer

Identifiers

PMID38039183
PMCPMC10873909

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.