SynthesisAnnals of surgical oncology2024
Physical Prehabilitation in Patients who Underwent Major Abdominal Surgery: A Comprehensive Systematic Review and Component Network Meta-Analysis Using GRADE and CINeMA Approach.
Synthesis in Annals of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Impact of Prehabilitation in Major Gastrointestinal Oncological Surgery: a Systematic Review.Journal of gastrointestinal cancer · 2025Pooled it
- [Prehabilitation for nononcological patients in visceral surgery].Chirurgie (Heidelberg, Germany) · 2025Pooled it
- Prehabilitation Outcomes in Surgical Oncology Patients Undergoing Major Abdominal Surgery: A Meta-analysis of Randomized Control Trials.Annals of surgical oncology · 2025Pooled it
- Relative efficacy of prehabilitation interventions and their components: systematic review with network and component network meta-analyses of randomised controlled trials.BMJ (Clinical research ed.) · 2025Pooled it
- Effect of improved preoperative activity levels and smoking cessation on ventral hernia repair outcomes.Surgical endoscopy · 2026Article
- Preoperative physical exercise training for people scheduled for major abdominal surgery.The Cochrane database of systematic reviews · 2026Article
- Consensus Guidelines on Perioperative Care in Primary Retroperitoneal Sarcoma Surgery.Annals of surgical oncology · 2026Article
- ASO Author Reflections: Enhanced Recovery in Retroperitoneal Sarcoma Surgery-From Concept to Consensus.Annals of surgical oncology · 2026Article
- [Special considerations in geriatric anesthesiology : Aspects of perioperative management in older adults].Zeitschrift fur Gerontologie und Geriatrie · 2026Review
- Non-pharmacological perioperative interventions to prevent postoperative pulmonary complications after abdominal surgery: a protocol for systematic review and meta-analysis.Systematic reviews · 2026Article
- Perioperative respiratory rehabilitation: evolving concepts and clinical applications.Anesthesia and pain medicine · 2026Review
- Article
- Perioperative nutritional support in patients undergoing gastrointestinal surgery: Current views with an emphasis on prehabilitation efforts.World journal of gastrointestinal surgery · 2025Article
- Review
- [Special considerations in geriatric anesthesiology : Aspects of perioperative management in older adults].Die Anaesthesiologie · 2025Review
- Review
- Prehabilitation in preparation for surgery.BMJ medicineReview
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhysical prehabilitation is recommended before major abdominal surgery to ameliorate short-term outcomes.
methodsA frequentist, random-effects network meta-analysis (NMA) was performed to clarify which type of preoperative physical activity among aerobic exercise (AE), inspiratory muscle training (IMT), and resistance training produces benefits in patients who underwent major abdominal surgery. The surface under the P-score, odds ratio (OR), or mean difference (MD) with a 95% confidence interval (CI) were reported. The results were adjusted by using the component network approach. The critical endpoints were overall and major morbidity rate and mortality rate. The important but not critical endpoints were the length of stay (LOS) and pneumonia.
resultsThe meta-analysis included 25 studies. The best approaches for overall morbidity rate were AE and AE + IMT (OR = 0.61, p-score = 0.76, and OR = 0.66, p-score = 0.68). The best approaches for pneumonia were AE + IMT and AE (OR = 0.21, p-score = 0.91, and OR = 0.52, p-score = 0.68). The component analysis confirmed that the best incremental OR (0.30; 95% CI 0.12-0.74) could be obtained using AE + IMT. The best approach for LOS was AE alone (MD - 1.63 days; 95% CI - 3.43 to 0.18). The best combination of components was AE + IMT (MD - 1.70; 95% CI - 2.06 to - 1.27).
conclusionsPhysical prehabilitation reduces the overall morbidity rate, pneumonia, and length of stay. The most relevant effect of prehabilitation requires the simultaneous use of AE and IMT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.