Evidence map›Paper›PMID 38038490›Full record

ReviewJournal of the American Geriatrics Society2024

Medication use quality and safety in older adults: 2022 update.

Shelly L Gray, Nicole Brandt, Kenneth E Schmader, Joseph T Hanlon

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American Geriatrics Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. [Functional assessment and medication in older adults].Innere Medizin (Heidelberg, Germany) · 2026
    Article
  2. Article
  3. Toward a Medication Information Literacy Indicator System for Older Adults: A Delphi Study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Shelly L GrayPlein Center for Geriatric Pharmacy Research, Education and Outreach, School of Pharmacy, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-5507-1859
Nicole BrandtPeter Lamy Center on Drug Therapy and Aging, School of Pharmacy, University of Maryland, Baltimore, Maryland, USA.
Kenneth E SchmaderDepartment of Medicine (Geriatrics), School of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Joseph T HanlonGeriatric Research, Education, and Clinical Center, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA.
Geriatric Research Education and Clinical Center · USUniversity of Maryland, Baltimore · USUniversity of Washington · US

Funding

Translational pharmacoepidemiology: neuroprotection and neurotoxicity of antihypertensives and strong anticholinergicsU19AG066567 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI CHRISTOPHER DIRK KEENE · 2021 to 2026
$80.4M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI CATHLEEN S COLON-EMERIC, Susan Nicole Hastings · 2006 to 2026
$24.6M
U.S. Deprescribing Research NetworkR24AG064025 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BOYD, CYNTHIA MELINDA, STEINMAN, MICHAEL A. · 2019 to 2023
$9.9M
Prescribing trends and associated outcomes of antiepileptic drugs and other psychoactive medications in US nursing homes surrounding the COVID-19 pandemicR01AG074358 · NIA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Jonathan David Winter · 2022 to 2026
$3.6M
Reducing CNS-active Medications to Prevent Falls and Injuries in Older AdultsU01CE002967 · CE · UNIVERSITY OF WASHINGTON · PI GRAY, SHELLY L, PHELAN, ELIZABETH ANNE · 2018 to 2021
$2.9M
Engaging Patients to Promote DeprescribingI01HX002798 · VA · VA BOSTON HEALTH CARE SYSTEM · PI LINSKY, AMY · 2020 to 2023
–
ACL HHS U01CE002967CDC HHS U01CD002967HSRD VA I01 HX002798NCIPC CDC HHS U01 CE002967NIA NIH HHS P30 AG028716NIA NIH HHS P30AG028716NIA NIH HHS R01AG07005NIA NIH HHS R01 AG074358NIA NIH HHS R01AG074358NIA NIH HHS R24 AG064025NIA NIH HHS R24AG064025-1NIA NIH HHS U19 AG066567NIA NIH HHS U19AG066567Patient-Centered Outcomes Research Institute 21121-UMD
6 · The paper itself

Abstract

Improving the quality of medication use and medication safety are important priorities for healthcare providers who care for older adults. The objective of this article was to identify four exemplary articles with this focus in 2022. We selected high-quality studies from an OVID search and hand searching of major high impact journals that advanced the field of research forward. The chosen articles cover domains related to deprescribing, medication safety, and optimizing medication use. The MedSafer Study, a cluster randomized clinical trial in Canada, evaluated whether patient specific deprescribing reports generated by electronic decision support software resulted in reduced adverse drug events in the 30 days post hospital discharge in older adults (domain: deprescribing). The second study, a retrospective cohort study using data from Premier Healthcare Database, examined in-hospital adverse clinical events associated with perioperative gabapentin use among older adults undergoing major surgery (domain: medication safety). The third study used an open-label parallel controlled trial in 39 Australian aged-care facilities to examine the effectiveness of a pharmacist-led intervention to reduce medication-induced deterioration and adverse reactions (domain: optimizing medication use). Lastly, the fourth study engaged experts in a Delphi method process to develop a consensus list of clinically important prescribing cascades that adversely affect older persons' health to aid clinicians to identify, prevent, and manage prescribing cascades (domain: optimizing medication use). Collectively, this review succinctly highlights pertinent topics related to promoting safe use of medications and promotes awareness of optimizing older adults' medication regimens.

Indexed as

DeprescriptionsAgedAged, 80 and overCanadaDrug-Related Side Effects and Adverse ReactionsHumansPatient SafetyRetrospective Studies80 years and overageddeprescribinginappropriate prescribingmedication‐related problemspolypharmacy

Identifiers

PMID38038490
PMCPMC11090755
OpenAlexW4389219422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.