Evidence map›Paper›PMID 38038451›Full record

ArticleMicrobiology spectrum2024

Joint application of metagenomic next-generation sequencing and histopathological examination for the diagnosis of pulmonary infectious disease.

Linhui Yang, Kaige Wang, Yalun Li, Weimin Li, Dan Liu

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Linhui Yang *Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University , Chengdu, China.ORCID 0009-0007-9669-3380
Kaige Wang *Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University , Chengdu, China.
Yalun LiDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University , Chengdu, China.
Weimin LiDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University , Chengdu, China.ORCID 0000-0003-0985-0311
Dan LiuDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University , Chengdu, China.ORCID 0000-0002-6618-0150
Sichuan University · CN

Funding

MOST | National Natural Science Foundation of China (NSFC) 82173182Science and Technology Program of Sichuan, China 2020YFS0572
6 · The paper itself

Abstract

importanceThe diagnosis of some pulmonary infectious diseases and their pathogens is very difficult. A more precise diagnosis of pulmonary infectious diseases can help clinicians use proper antibiotics as well as reduce the development of drug-resistant bacteria. In this study, we performed both mNGS and pathology on lung puncture biopsy tissue from patients and found that combined mNGS and histopathology testing was significantly more effective than histopathology testing alone in detecting infectious diseases and identifying infectious diseases. In addition, the combined approach improves the detection rate of pathogenic microorganisms in infectious diseases and can be used to guide precision clinical treatment.

Indexed as

Communicable DiseasesAnti-Bacterial AgentsHigh-Throughput Nucleotide SequencingHumansLungMetagenomeMetagenomicsAnti-Bacterial Agentshistopathologyinfectious diseasemicrobiologymNGSpulmonary

Identifiers

PMID38038451
PMCPMC10783098
OpenAlexW4389223273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.