Evidence map›Paper›PMID 38037906›Full record

ArticleCurrent organic synthesis2024

Recent Advancements in the Synthesis of α-fluoroalkylated Azine-derived Heterocycles through Direct Fluorination.

Oksana M Shavrina, Yuliya V Rassukana, Petro P Onysko

Abstract read
PubMed Publisher
In one paragraph

Article in Current organic synthesis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Oksana M ShavrinaDepartment of Chemistry of Organoelement Compounds, Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Akademika Kukharya str., Kyiv, 02660, Ukraine.ORCID 0009-0001-2751-1922
Yuliya V RassukanaDepartment of Chemistry of Organoelement Compounds, Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Akademika Kukharya str., Kyiv, 02660, Ukraine.
Petro P OnyskoDepartment of Chemistry of Organoelement Compounds, Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Akademika Kukharya str., Kyiv, 02660, Ukraine.ORCID 0000-0002-6137-2778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The review highlights recent advancements in the synthesis of α-fluoro and α,α- difluoroalkylated azines, focusing on two main approaches. The first approach involves nucleophilic deoxofluorination, wherein α-hydroxy- or α-oxoalkylated azines are treated with diethylaminosulfur trifluoride or other S-F reagents to introduce fluorine atoms. The second approach employs direct electrophilic benzylic fluorination, whereby alkylazines undergo fluorination using N-F reagents. Both methods provide flexibility in designing and synthesizing fluoroalkylated heterocycles.

Indexed as

Alkylazinesdiethylaminosulfur trifluoride.difluoromethylfluorinationfluoromethylN-F fluorinating agentspyridinespyrimidines

Identifiers

PMID38037906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.