Evidence map›Paper›PMID 38037829›Full record

ArticleInquiry : a journal of medical care organization, provision and financing

Comparative Effectiveness of 2 Chlorhexidine Gluconate-Containing Dressings in Reducing Central Line-Associated Bloodstream Infections, Hospital Stay, and Costs.

Yuefeng Hou, Leah Griffin, Stéphanie F Bernatchez, Joseph Hommes, Tarja Kärpänen, Maria Palka-Santini

Open access · goldAbstract read
In one paragraph

Article in Inquiry : a journal of medical care organization, provision and financing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yuefeng Hou3M Health Care, 3M Company, Austin, TX, USA.ORCID 0000-0002-4986-8922
Leah Griffin3M Health Care, 3M Company, San Antonio, TX, USA.
Stéphanie F Bernatchez3M Health Care, 3M Company, St. Paul, MN, USA.ORCID 0000-0002-2908-4581
Joseph Hommes3M Health Care, 3M Company, St. Paul, MN, USA.
Tarja Kärpänen3M Health Care, 3M Deutschland GmbH, Neuss, Germany.
Maria Palka-Santini3M Health Care, 3M Deutschland GmbH, Neuss, Germany.
3M (Germany) · DESSM Health Care · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlorhexidine gluconate (CHG)-containing dressings are recommended to prevent central line associated bloodstream infections (CLABSIs) and other catheter-related infections. This study compared the effect of 2 CHG dressings on CLABSI, cost of care, and contact dermatitis. A retrospective analysis was conducted using the Premier Healthcare Database of hospitalized patients (n = 53 149) with central venous catheters (CVCs) and receiving either a transparent CHG gel dressing (n = 14 488) or an opaque CHG sponge dressing (n = 38 661) between January 2019 and September 2020. Two cohorts (n = 14 488 each), CHG-Gel and CHG-Sponge, were matched 1:1 using a propensity score method on 33 patient and facility characteristics. CLABSI and contact dermatitis rates, hospital length of stay (LOS), and hospitalization costs were compared using mixed-effect multiple regression. This approach effectively controlled for random clustering effects across hospitals and patients' Diagnosis-Related Group (DRG) classifications. CHG gel dressings were associated with a 41% decrease in CLABSI rates (

Indexed as

Anti-Infective Agents, LocalCatheterization, Central VenousDermatitis, ContactSepsisBandagesChlorhexidineComparative Effectiveness ResearchHumansLength of StayRetrospective StudiesAnti-Infective Agents, LocalChlorhexidinechlorhexidine gluconatecomparative studyinpatientoutcome researchPremier Healthcare Databasereal world evidence

Identifiers

PMID38037829
PMCPMC10693226
OpenAlexW4389237396

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.