Evidence map›Paper›PMID 38037650›Full record

ArticleSynOpen (2017)2023

Amide N-C Bond Activation: A Graphical Overview of Acyl and Decarbonylative Coupling.

Chengwei Liu, Michal Szostak

Abstract read
In one paragraph

Article in SynOpen (2017), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. "Cut-and-Sew" Reactions of β-Lactams via C-C Bond Activation.Journal of the American Chemical Society · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chengwei LiuDepartment of Chemistry, Shanghai University, 99 Shangda Road, Shanghai 200444, China.
Michal SzostakDepartment of Chemistry, Rutgers University, 73 Warren Street, Newark, NJ 07102, USA.

Funding

Catalytic Methods for Organic SynthesisR35GM133326 · NIGMS · RUTGERS THE STATE UNIV OF NJ NEWARK · PI Michal Szostak · 2019 to 2026
$2.7M
NIGMS NIH HHS R35 GM133326
6 · The paper itself

Abstract

This Graphical Review provides an overview of amide bond activation achieved by selective oxidative addition of the N-C(O) acyl bond to transition metals and nucleophilic acyl addition, resulting in acyl and decarbonylative coupling together with key mechanistic details pertaining to amide bond distortion underlying this reactivity manifold.

Indexed as

acyl additionacyl couplingamide bond activationcatalysisC–N activationdecarbonylative coupling

Identifiers

PMID38037650
PMCPMC10686541

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.