Evidence map›Paper›PMID 38037556›Full record

ArticleJournal of liver transplantation2023

Vascular thrombosis after pediatric liver transplantation: Is prevention achievable?

Mercedes Martinez, Elise Kang, Fernando Beltramo, Michael Nares, Asumthia Jeyapalan, Alicia Alcamo, Alexandra Monde, Leslie Ridall, Sameer Kamath, Kristina Betters and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of liver transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 1 country.

Mercedes MartinezColumbia University Irving Medical Center, Department of Pediatrics, New York, USA.
Elise KangColumbia University Irving Medical Center, Department of Pediatrics, New York, USA.
Fernando BeltramoChildren's Hospital of Los Angeles, Department of Anesthesiology Critical Care, Los Angeles, USA.
Michael NaresUniversity of Miami Miller School of Medicine, Department of Pediatrics, Miami, USA.
Asumthia JeyapalanUniversity of Miami Miller School of Medicine, Department of Pediatrics, Miami, USA.
Alicia AlcamoChildren's Hospital of Philadelphia, Department of Critical Care Medicine, Philadelphia, USA.
Alexandra MondeGeorgetown University Hospital, Department of Pediatrics, Washington DC, USA.
Leslie RidallUniversity of Colorado School of Medicine, Department of Pediatrics, Aurora, USA.
Sameer KamathDuke University, Department of Pediatrics, Durham, USA.
Kristina BettersVanderbilt University, Department of Pediatrics, Nashville, USA.
Courtney RowanIndiana University School of Medicine, Department of Pediatrics, Indianapolis, USA.
Richard Shane MangusIndiana University School of Medicine, Department of Surgery, Indianapolis, USA.
Shubhi KaushikMount Sinai School of Medicine, Department of Pediatrics, New York, USA.
Matt ZinterUniversity of California San Francisco, Department of Pediatrics, San Francisco, USA.
Joseph ReschUniversity of Minnesota, Department of Pediatrics, Minneapolis, USA.
Danielle MaueIndiana University School of Medicine, Department of Pediatrics, Indianapolis, USA.
Indiana University School of MedicineColumbia University Irving Medical Center · USUniversity of Miami · USChildren's Hospital at Montefiore · USChildren's Hospital of Los Angeles · USChildren's Hospital of Philadelphia · USDuke University · USGeorgetown University · USUniversity of California, San Francisco · USUniversity of Colorado Denver · USUniversity of Minnesota · USVanderbilt University · US

Funding

Pathobiologic Transcriptional Signatures of Pulmonary Complications in Pediatric Hematopoietic Cellular TransplantationK23HL146936 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ZINTER, MATTHEW SCOTT · 2020 to 2024
$980k
Prognostic biomarkers for respiratory failure post hematopoietic cell transplantationK23HL150244 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI ROWAN, COURTNEY · 2020 to 2024
$899k
NHLBI NIH HHS K23 HL146936NHLBI NIH HHS K23 HL150244
6 · The paper itself

Abstract

Background: Vascular thromboses (VT) are life-threatening events after pediatric liver transplantation (LT). Single-center studies have identified risk factors for intra-abdominal VT, but large-scale pediatric studies are lacking. Methods: This multicenter retrospective cohort study of isolated pediatric LT recipients assessed pre- and perioperative variables to determine VT risk factors and anticoagulation-associated bleeding complications. Results: Within seven postoperative days, 31/331 (9.37%) patients developed intra-abdominal VT. Open fascia occurred more commonly in patients with VT (51.61 vs 23.33%) and remained the only independent risk factor in multivariable analysis (OR = 2.84, Conclusions: Prophylactic anticoagulation did not increase bleeding complications in this cohort. The only independent factor associated with VT was open fascia, likely a graft/recipient size mismatch surrogate, supporting the need to improve surgical techniques to prevent VT that may not be modifiable with anticoagulation.

Indexed as

Hepatic artery thrombosisPediatric liver transplantationPortal vein thrombosisVascular complications

Identifiers

PMID38037556
PMCPMC10686788
OpenAlexW4387783653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.