Evidence map›Paper›PMID 38037548›Full record

ArticleJournal of gynecologic oncology2024

Impact of peritoneal vaginoplasty combined with radical hysterectomy on the quality of sexual life for patients with early-stage cervical cancer: trial protocol for a multi-center superiority randomized controlled trial.

Shimin Yang, Yan Ding, Huaifang Li, Sufang Wu, Weiwei Feng, Yudong Wang, Xipeng Wang, Keqin Hua

Open access · diamondAbstract readClinical Trial Protocol
In one paragraph

Article in Journal of gynecologic oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Shimin Yang *Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.ORCID 0009-0009-3052-663X
Yan Ding *Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.ORCID 0009-0001-3629-486X
Huaifang LiDepartment of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji University, Shanghai, China.ORCID 0000-0002-9496-7145
Sufang WuDepartment of Obstetrics and Gynecology, Shanghai General Hospital of Shanghai Jiaotong University School of Medicine, Shanghai, China.ORCID 0000-0003-1216-4814
Weiwei FengDepartment of Obstetrics and Gynecology, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.ORCID 0000-0002-0685-9479
Yudong WangDepartment of Gynecologic Oncology, The International Peace Maternity & Child Health Hospital (IPMCH) of China Welfare Institute (CWI), Shanghai, China.ORCID 0000-0002-9455-4471
Xipeng WangDepartment of Obstetrics and Gynecology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.ORCID 0000-0002-7555-4185
Keqin HuaDepartment of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China. huakeqinjiaoshou@163.com.ORCID 0000-0001-5359-8841
Obstetrics and Gynecology Hospital of Fudan University · CNInternational Peace Maternity & Child Health Hospital · CNRuijin Hospital · CNShanghai Jiao Tong University · CNTongji University · CNXinHua Hospital · CN

Funding

Clinical Research Plan of SHDC SHDC2020CR1045B
6 · The paper itself

Abstract

backgroundRadical hysterectomy (RH) is commonly used to treat early-stage cervical cancer in women of childbearing age and sexual dysfunction due to postoperative vaginal shortening is a major concern. The impact of intraoperative vaginoplasty on prognosis and quality of sexual life in patients with early-stage cervical cancer remains controversial and lacks high-level evidence. However, there are few reports on vaginoplasty after RH to lengthen vagina in patients. This prospective, multi-center, randomized controlled trial aims to explore the impact of peritoneal vaginoplasty with or without ovarian transposition after laparoscopic RH on sexual dysfunction in patients with early-stage cervical cancer.

methodsEligible patients will be randomly assigned (1:1) to receive peritoneal vaginoplasty or not. The primary evaluation indicators are female sexual function index (FSFI) and male sexual satisfaction scale. The secondary evaluation indicators include EORTC QLQ-CX24, 2-year overall survival (OS), 5-year OS, 2-year progression-free survival (PFS), 5-year PFS and surgery-related complications. The trial will enroll 368 patients from 6 hospitals in China over a 3-year period and follow up for 5 years.

trial registrationChinese Clinical Trial Registry Identifier: ChiCTR2000040610.

Indexed as

HysterectomyQuality of LifeUterine Cervical NeoplasmsVaginaAdultEquivalence Trials as TopicFemaleHumansMiddle AgedMulticenter Studies as TopicNeoplasm StagingPeritoneumProspective StudiesRandomized Controlled Trials as TopicSexual Dysfunction, PhysiologicalCervical CancerPeritoneumRadical HysterectomySexual FunctionVaginoplasty

Identifiers

PMID38037548
PMCPMC11107286
OpenAlexW4389107560

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.