ReviewClinical hypertension2023
Arterial stiffness and hypertension.
Review in Clinical hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
151 citing papers in PubMed, 5 syntheses or guidelines pooled it, 191 citations in OpenAlex.
- Comparative effectiveness of various exercise modalities on arterial stiffness and endothelial function in older adults: a systematic review and network meta-analysis of randomised controlled trials.Frontiers in cardiovascular medicine · 2026Pooled it
- Exploring the role of oxidative stress in retinal vein occlusion: an updated and comprehensive review on the pathophysiology and treatment perspectives.International ophthalmology · 2025Pooled it
- Impact of living kidney donation on blood pressure and arterial stiffness: Systematic review and meta-analysis.PloS one · 2025Pooled it
- Mapping arterial stiffness metabolic biomarkers: a bibliometric analysis.Frontiers in medicine · 2025Pooled it
- Effects of time-restricted eating without caloric restriction on blood pressure and cardiometabolic profile in non-diabetic adults: a systematic review and meta-analysis of randomized controlled trials.Frontiers in nutrition · 2025Pooled it
- Pulse pressure as a predictor of Alzheimer's disease biomarkers and cognitive decline: The moderating role of APOE ε4.The journal of prevention of Alzheimer's disease · 2025Trial
- The correlation between serum endothelin-1 levels and aortic stiffness in patients with non-dialysis chronic kidney disease.Renal failure · 2026Article
- Risk factors for community-acquired pressure injuries: Findings from a large-scale Asian case-control study.International journal of nursing studies advances · 2026Article
- Hypertension: a missing piece in HFpEF?Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- Six weeks stretching of lower limbs lowers blood pressure in hypertensive individuals.European journal of applied physiology · 2026Article
- Association of Estimated Pulse Wave Velocity with Chronic Kidney Disease Risk: A Machine Learning Analysis Based on NHANES and CHARLS.Healthcare (Basel, Switzerland) · 2026Article
- Association between HIV infection and arterial stiffness: A population-based cross-sectional study from Rakai, South Western Uganda.Atherosclerosis plus · 2026Article
- Blood pressure variability in daily life: comparing individuals with cervical and upper-thoracic spinal cord injury to non-injured controls.Journal of human hypertension · 2026Article
- Blood pressure variability and frailty: mechanisms, evidence, and clinical implications.International urology and nephrology · 2026Review
- Clinical Relevance and Potential Applications of Brachial-Ankle Pulse Wave Velocity: Current Evidence and Future Perspectives.Journal of clinical medicine · 2026Review
- Lipoprotein(a) and Hypertension-Mediated Organ Damage in Patients with Essential Hypertension: Associations with Carotid Plaque and Impaired Nocturnal Blood Pressure Dipping.Medicina (Kaunas, Lithuania) · 2026Article
- Unmasking the role of hypertension in atherosclerosis among patients with obesity: a cardiometabolic dysfunction perspective.International journal of obesity (2005) · 2026Observational
- DASH Diet, Dietary Nitrate, and Nitric Oxide Bioavailability: Implications for Endothelial Dysfunction and Hypertension in Older Adults.Molecular nutrition & food research · 2026Review
- Article
- Exposure to bisphenols and phthalates and arterial stiffness in women of reproductive age: a New York City cohort analysis.Environment international · 2026Article
91 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and renin-angiotensin-aldosterone system (RAAS) activation. Hypertension also increases collagen fiber production and accelerates elastin fiber degradation. Stiffened arteries struggle with BP changes, raising systolic BP and pulse pressure. The resulting increased systolic pressure further hardens arteries, creating a harmful cycle of inflammation and calcification. Arterial stiffness data can predict target organ damage and future cardiovascular events in hypertensive patients. Thus, early detection of arterial stiffness aids in initiating preventive measures and treatment plans to protect against progression of vascular damage. While various methods exist for measuring arterial stiffness, pulse wave velocity is a non-invasive, simple measurement method that maximizes effectiveness. Healthy lifestyle changes, RAAS blockers, and statins are known to reduce arterial stiffness. Further research is needed to ascertain if improving arterial stiffness will enhance prognosis in hypertensive patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.