ArticleLipids in health and disease2023
Associations of serum carotenoids with visceral adiposity index and lipid accumulation product: a cross-sectional study based on NHANES 2001-2006.
Article in Lipids in health and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07457515 (Analysis of the Transmission of Overweight/Obesity in the Mother-breastmilk-child Triad in Relation to Maternal Cardiometabolic Status and Diet), which is not on this map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analysis of the Transmission of Overweight/Obesity in the Mother-breastmilk-child Triad in Relation to Maternal Cardiometabolic Status and Diet
Who cites it
17 citing papers in PubMed.
- Phytocompounds That Target White Adipose Tissue for Weight Loss: A Review Spanning From Ucp1 Induction in Rodents to Human Clinical Trials.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Examining Demographic Variables Associated with Fruit and Vegetable Intake and Skin Yellowness.Nutrients · 2026Article
- Blood Serum From Obese Women Raises ROS Production by Neural Stem Cells.Developmental neurobiology · 2026Article
- Association of visceral obesity with Helicobacter pylori seropositivity and mortality in US adults.BMC infectious diseases · 2026Article
- A Cross-sectional Data Analysis between Serum Total Bilirubin and Potential Obesity Indices in US Adults.Current molecular medicine · 2026Article
- Visceral lipid accumulation and lipid accumulation product outperform insulin resistance score for metabolic syndrome prediction in Northern Chinese adults: validation through AUC comparison and decision curve analysis.BMC endocrine disorders · 2025Article
- Inverse relationship between serum carotenoid levels and obesity prevalence in children and adolescents: a nationwide cross-sectional analysis.BMC pediatrics · 2025Article
- Visceral adiposity index as a predictor of metabolic dysfunction-associated steatotic liver disease: a cross-sectional study.BMC gastroenterology · 2025Article
- Association between lipid accumulation products and relative handgrip strength: a large population-based study.Scientific reports · 2025Article
- Article
- Association between cardiometabolic Index and obstructive sleep apnea and the mediating role of smoking: a cross-sectional study.Frontiers in endocrinology · 2025Article
- Metabolomics signatures of sweetened beverages and added sugar are related to anthropometric measures of adiposity in young individuals: results from a cohort study.The American journal of clinical nutrition · 2024Article
- Association between severe headache or migraine and lipid accumulation product and visceral adiposity index in adults: a cross-sectional study from NHANES.Lipids in health and disease · 2024Article
- Association between obstructive sleep apnea and visceral adiposity index and lipid accumulation product: NHANES 2015-2018.Lipids in health and disease · 2024Article
- Micronutrient status, food security, anaemia,Frontiers in nutrition · 2024Article
- Association between serum carotenoids levels and severe headache or migraine in adults: a cross-sectional study from NHANES.Frontiers in nutrition · 2024Article
- Association between visceral adiposity index and chronic obstructive pulmonary disease: A cross-sectional analysis.Science progressArticle
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7 authors.
Funding
Abstract
backgroundVisceral adiposity index (VAI) and lipid accumulation product (LAP) are comprehensive indicators to evaluate visceral fat and determine the metabolic health of individuals. Carotenoids are a group of naturally occurring antioxidants associated with several diseases. The purpose of this investigation was to explore the association between serum carotenoid concentration and VAI or LAP.
methodsThe data were obtained from the National Health and Nutrition Examination Survey between 2001 and 2006. The levels of serum carotenoids were evaluated using high-performance liquid chromatography. Multivariate linear regression models were employed to investigate the relationship between levels of serum carotenoids and VAI or LAP. The potential non-linear relationship was determined using threshold effect analysis and fitted smoothing curves. Stratification analysis was performed to investigate the potential modifying factors.
resultsIn total, 5,084 participants were included in this population-based investigation. In the multivariate linear regressions, compared to the lowest quartiles of serum carotenoids, the highest quartiles were significantly associated with VAI, and the effect size (β) and 95% CI was - 0.98 (- 1.34, - 0.62) for α-carotene, - 1.39 (- 1.77, - 1.00) for β-carotene, - 0.79 (- 1.18, - 0.41) for β-cryptoxanthin, - 0.68 (- 0.96, - 0.39) for lutein/zeaxanthin, and - 0.88 (- 1.50, - 0.27) for trans-lycopene. Using piece-wise linear regression models, non-linear relationships were found between β-carotene and trans-lycopene and VAI with an inflection point of 2.44 (log2-transformed, ug/dL) and 3.80 (log2-transformed, ug/dL), respectively. The results indicated that α-carotene, β-cryptoxanthin, and lutein/zeaxanthin were linearly associated with VAI. An inverse association was also found between serum carotenoids and LAP after complete adjustments.
conclusionThis study revealed that several serum carotenoids were associated with VAI or LAP among the general American population. Further large prospective investigations are warranted to support this finding.
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