Evidence map›Paper›PMID 38036951›Full record

ArticleBMC nephrology2023

Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury.

Jorge Alberto Menegasso Vieira, Isabel Cristina Reinheimer, Amanda Corrêa Dos Santos, Fernando Kowarick Halperin, Luiza Aguirre Susin, Lia Portella Staub, Raquel Jaqueline Eder Ribeiro, Julia Braga da Silveira, Lucas Friedrich Fontoura, Diego Candido de Souza and 4 more

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In one paragraph

Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Jorge Alberto Menegasso VieiraDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil. jorge.vieira@edu.pucrs.br.ORCID 0000-0001-9922-0836
Isabel Cristina ReinheimerDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.
Amanda Corrêa Dos SantosDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.
Fernando Kowarick HalperinDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.
Luiza Aguirre SusinDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.
Lia Portella StaubDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.
Raquel Jaqueline Eder RibeiroDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.
Julia Braga da SilveiraDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.
Lucas Friedrich FontouraAcademic Master's and Doctorate Degree in Health Sciences, Universidade de Caxias do Sul (UCS), Street Francisco Getúlio Vargas, 1130, Caxias do Sul, Rio Grande do Sul, 95070-560, Brazil.
Diego Candido de SouzaDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.
Karen Patrícia NunesAcademic Master's and Doctorate Degree in Health Sciences, Universidade de Caxias do Sul (UCS), Street Francisco Getúlio Vargas, 1130, Caxias do Sul, Rio Grande do Sul, 95070-560, Brazil.
Vandrea Carla de SouzaAcademic Master's and Doctorate Degree in Health Sciences, Universidade de Caxias do Sul (UCS), Street Francisco Getúlio Vargas, 1130, Caxias do Sul, Rio Grande do Sul, 95070-560, Brazil.
Luciano da Silva SelistreAcademic Master's and Doctorate Degree in Health Sciences, Universidade de Caxias do Sul (UCS), Street Francisco Getúlio Vargas, 1130, Caxias do Sul, Rio Grande do Sul, 95070-560, Brazil.
Carlos Eduardo Poli-de-FigueiredoDepartment: Nephrology Service, Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 - Escola de Medicina - Prédio 12, Porto Alegre, Rio Grande do Sul, CEP 90619-900, Brazil.ORCID 0000-0002-7333-8884
Pontifícia Universidade Católica do Rio Grande do Sul · BRUniversidade de Caxias do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProlonged hemodialysis (HD) is performed from 6 to 12 h and can last up to 24 h. To prevent system clotting some studies suggest that Regional Citrate Anticoagulation (RCA) use reduces bleeding rates relative to systemic heparin. However, there may be difficulties in the patient's clinical management and completing the prescribed HD with Genius system using RCA.

objectiveTo analyze safety Quality Indicators (IQs) and follow up on prolonged HD with 4% sodium citrate solution in a Genius® hybrid system.

methodsThis is a retrospective cohort conducted in an intensive care unit.

results53 random sessions of prolonged HD with 4% sodium citrate solution of critically ill patients with AKI assessed. Evaluated safety indicators were dysnatremia and metabolic alkalosis, observed in 15% and 9.4% of the sessions, respectively. Indicators of effectiveness were system clotting which occurred in 17.3%, and the minimum completion of the prescribed HD time, which was 75.5%.

conclusionThe assessment of the indicators showed that the use of RCA with a 4% sodium citrate solution in prolonged HD with the Genius system in critically ill patients with AKI can be performed in a simple, safe, and effective way.

Indexed as

Acute Kidney InjuryCitric AcidAnticoagulantsCitratesCritical IllnessHeparinHumansQuality Indicators, Health CareRenal DialysisRetrospective StudiesSodium CitrateAnticoagulantsCitratesCitric AcidHeparinSodium CitrateHybrid renal replacement therapyRegional citrate anticoagulationSLED techniqueSlow extended dialysis modeSustained low-efficiency dialysis

Identifiers

PMID38036951
PMCPMC10691098
OpenAlexW4389206919

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.