SynthesisJournal of neurology2024
Blood pressure variability predicts poor outcomes in acute stroke patients without thrombolysis: a systematic review and meta-analysis.
Synthesis in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Association between post-thrombectomy blood pressure trajectories and clinical outcomes in hypertensive patients with acute ischemic stroke: a retrospective cohort study.Journal of human hypertension · 2026Article
- Blood Pressure Variability in Acute Ischemic Stroke: Current Evidence, Measurement Challenges, and Future Directions.Journal of clinical hypertension (Greenwich, Conn.) · 2026Review
- Blood pressure variability and the risk of post-stroke cognitive impairment following atrial fibrillation related acute ischemic stroke.Clinical hypertension · 2026Article
- Intensive vs. standard nurse-supervised blood pressure monitoring and intensive care utilization in acute hypertensive encephalopathy: a single-center retrospective cohort study.Frontiers in medicine · 2026Article
- Blood Pressure Variability and 90-Day Functional Outcome in Branch Atheromatous Disease-Related Stroke: A Multicenter Prospective Study.Journal of clinical hypertension (Greenwich, Conn.) · 2025Observational
- Review
- Observational
- Blood Pressure Variability in Acute Stroke: A Narrative Review.Journal of clinical medicine · 2024Review
- Association between oral microbial nitrate metabolism and poor prognosis in acute ischemic stroke patients with a history of hypertension.Journal of oral microbiology · 2024Article
- Correlation of glymphatic system abnormalities with Parkinson's disease progression: a clinical study based on non-invasive fMRI.Journal of neurology · 2024Article
- The constrained-disorder principle defines the functions of systems in nature.Frontiers in network physiology · 2024Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStroke is a significant medical condition, and blood pressure stands out as the most prevalent treatable risk factor associated with it. Researches link blood pressure variability (BPV) with stroke; however, the specific relationship between with the outcomes of stroke patients remains unclear. As blood pressure variability and mean blood pressure are interrelated, it remains uncertain whether BPV adds additional information to understanding the outcome of acute stroke patients.
objectiveTo systematically review studies investigating the association between blood pressure variability and prognosis in acute stroke patients.
methodsEmbase, PubMed, Web of Science, and the Cochrane Library were searched for English language full-text articles from the inception to 1 January 2023. Stroke patients aged ≥ 18 years were included in this analysis. Stroke types were not restricted.
resultsThis meta-analysis shows that higher systolic blood pressure variability is linked to a higher risk of poor outcome, including function disability, mortality, early neurological deterioration, and stroke recurrence, among acute stroke patients without thrombolysis. A higher diastolic blood pressure variability is linked with to a higher risk of mortality and functional disability.
conclusionsThis review reveals that blood pressure variability is a novel and clinically relevant risk factor for stroke patients' outcome. Future studies should investigate how best to measure and define BPV in acute stroke. Larger studies are warranted to provide more robust evidence in this area.
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Registered trials
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