ArticleNature neuroscience2023
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD.
Article in Nature neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Semantic encoding of trauma memories in the hippocampus among individuals with PTSD.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Trial
- Severe PTSD symptoms magnify episodic memory-encoding deficits and amygdala-ACC attenuation during unpredictable threat in male combat veterans.Molecular psychiatry · 2026Article
- Reconciling hippocampal semantic representations of traumatic memory in PTSD.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Reducing PTSD symptoms through unconscious intervention.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Microstructural Integrity of Hippocampal-Posterior Cortical White Matter Is Associated With Phenomenological Properties of Trauma-Related Intrusive Memories.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Effect of a stepped-care trauma rehabilitation programme for migrants in Germany: the 'NAT counselling intervention' study protocol for a naturalistic parallel group trial with a regression discontinuity design for quasi-randomization.BMC health services research · 2026Article
- Threading the Needle: Practical Considerations for Merging Theory-Driven Computational Psychiatry With Data-Driven Analytics to Enhance Precision Health at Scale.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Review
- Mapping the Cross-species Brain Connectivity Atlas and Hemispheric Asymmetry of the Temporal Pole in Humans and Macaques.Neuroscience bulletin · 2026Article
- RESET post-traumatic stress disorder: clinical protocol integrating reconsolidation, exposure, short-term emotional transformation.European journal of psychotraumatology · 2025Article
- Targeting memory of embedded positive verbal content indirectly modulates negative visual memory.iScience · 2025Article
- Dissociable Neural Connectome Mapping of Reward and Punishment Responsiveness in Young Adults: Associations with Genetic Variability and Neurotransmitter Profiles.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Unbarring the unbearable infinity: a bi-logic view on the experience of trauma.American journal of psychoanalysis · 2025Article
- Unraveling trauma memory: Differential functional connectivity profiles of anterior and posterior hippocampus in post-traumatic stress disorder and its dissociative subtype.Neuroimage. Reports · 2025Article
- Neuroplasticity in Post-Traumatic Stress Disorder.Revista de neurologia · 2025Review
- Assessing and alleviating state anxiety in large language models.NPJ digital medicine · 2025Article
- Decoding threat neurocircuitry representations during traumatic memory recall in PTSD.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Post-traumatic stress disorder: evolving conceptualization and evidence, and future research directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Characterizing the patient experience of physical restraint in psychiatric settings via a linguistic, sentiment, and metaphor analysis.Scientific reports · 2025Article
- Going Beyond Explicit Memories: Future Steps and Considerations in the Research of Symptom-Relevant Negative Autobiographical Memories in Anxiety Related Disorders.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2025Article
- Contribution of narrative therapy in reduction of anxiety, depression and PTSD among survivors of the genocide against the Tutsi in 1994 in Rwanda.PLOS mental health · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
For people with post-traumatic stress disorder (PTSD), recall of traumatic memories often displays as intrusions that differ profoundly from processing of 'regular' negative memories. These mnemonic features fueled theories speculating a unique cognitive state linked with traumatic memories. Yet, to date, little empirical evidence supports this view. Here we examined neural activity of patients with PTSD who were listening to narratives depicting their own memories. An intersubject representational similarity analysis of cross-subject semantic content and neural patterns revealed a differentiation in hippocampal representation by narrative type: semantically similar, sad autobiographical memories elicited similar neural representations across participants. By contrast, within the same individuals, semantically similar trauma memories were not represented similarly. Furthermore, we were able to decode memory type from hippocampal multivoxel patterns. Finally, individual symptom severity modulated semantic representation of the traumatic narratives in the posterior cingulate cortex. Taken together, these findings suggest that traumatic memories are an alternative cognitive entity that deviates from memory per se.
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