Evidence map›Paper›PMID 38036392›Full record

ArticleVaccine2024

The 2022 Vaccines Against Shigella and Enterotoxigenic Escherichia coli (VASE) Conference: Summary of breakout workshops.

Shahida Baqar, Aurelio Bonavia, A Louis Bourgeois, Joseph J Campo, Allison Clifford, Kurt Hanevik, Mateusz Hasso-Agopsowicz, William Hausdorff, Robert Kaminski, Calman A MacLennan and 12 more

Open access · hybridAbstract read
In one paragraph

Article in Vaccine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Burden ofBMJ global health · 2026
    Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 18 institutions in 7 countries.

Shahida BaqarUS National Institutes of Health, United States.
Aurelio BonaviaBill & Melinda Gates Medical Research Institute, United States.
A Louis BourgeoisPATH, United States.
Joseph J CampoAntigen Discovery, Inc, United States.
Allison CliffordPATH, United States. Electronic address: aclifford@path.org.
Kurt HanevikUniversity of Bergen, Norway; Norwegian National Advisory Unit for Tropical Infectious Diseases, Medical Department, Haukeland University Hospital, Norway.
Mateusz Hasso-AgopsowiczWorld Health Organization, Switzerland.
William HausdorffPATH, United States; Faculty of Medicine, Université Libre de Bruxelles, Belgium.
Robert KaminskiLatham BioPharm Group, United States.
Calman A MacLennanEnteric and Diarrheal Diseases, Bill & Melinda Gates Foundation, United Kingdom; The Jenner Institute, United Kingdom.
Nicholas MantisWadsworth Center, New York State Department of Health, United States.
Laura B MartinUS Pharmacopeial Convention, United States.
Richard OmoreKenya Medical Research Institute Center for Global Health Research, Kenya.
Marcela PasettiUniversity of Maryland, United States.
Patricia PavlinacUniversity of Washington, United States.
Armelle PhaliponInstitut Pasteur, France.
Frédéric PolyNaval Medical Research Command, United States.
Chad PorterNaval Medical Research Command, United States.
Maheshi N RamasamyOxford Vaccine Group, University of Oxford, United Kingdom.
Elizabeth T Rogawski McQuadeEmory University, United States.
Marcelo B SzteinUniversity of Maryland, United States.
Richard WalkerPATH, United States.
Program for Appropriate Technology in Health · USBill & Melinda Gates Foundation · USNaval Medical Research Command · USAntigen Discovery (United States) · USCentennial Medical Group · USEmory University · USInstitut Pasteur · FRKenya Medical Research Institute · KENational Institutes of Health · USUnited States Pharmacopeial Convention · USUniversité Libre de Bruxelles · BEUniversity of Bergen · NOUniversity of Maryland, Baltimore · USUniversity of Maryland, College Park · USUniversity of Oxford · GBUniversity of Washington · USWadsworth Center · USWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

The global public health nonprofit organization PATH hosted the third Vaccines Against Shigella and Enterotoxigenic Escherichia coli (VASE) Conference in Washington, DC, from November 29 to December 1, 2022. This international gathering focused on cutting-edge research related to the development of vaccines against neglected diarrheal pathogens including Shigella, enterotoxigenic Escherichia coli (ETEC), Campylobacter, and non-typhoidal Salmonella. In addition to the conference's plenary content, the agenda featured ten breakout workshops on topics of importance to the enteric vaccine field. This unique aspect of VASE Conferences allows focused groups of attendees to engage in in-depth discussions on subjects of interest to the enteric vaccine development community. In 2022, the workshops covered a range of topics. Two focused on the public health value of enteric vaccines, with one examining how to translate evidence into policy and the other on the value proposition of potential combination vaccines against bacterial enteric pathogens. Two more workshops explored new tools for the development and evaluation of vaccines, with the first on integrating antigen/antibody technologies for mucosal vaccine and immunoprophylactic development, and the second on adjuvants specifically for Shigella vaccines for children in low- and middle-income countries. Another pair of workshops covered the status of vaccines against two emerging enteric pathogens, Campylobacter and invasive non-typhoidal Salmonella. The remaining four workshops examined the assessment of vaccine impact on acute and long-term morbidity. These included discussions on the nature and severity of intestinal inflammation; cellular immunity and immunological memory in ETEC and Shigella infections; clinical and microbiologic endpoints for Shigella vaccine efficacy studies in children; and intricacies of protective immunity to enteric pathogens. This article provides a brief summary of the presentations and discussions at each workshop in order to share these sessions with the broader enteric vaccine field.

Indexed as

Enterotoxigenic Escherichia coliEscherichia coli InfectionsEscherichia coli VaccinesOligopeptidesShigellaShigella VaccinesChildDiarrheaHumansSalmonellaEscherichia coli VaccinesOligopeptidesShigella VaccinesVASE peptideCampylobacterEnteric diseasesEnterotoxigenic Escherichia coliInvasive non-typhoidal SalmonellaShigellaVaccine development

Identifiers

PMID38036392
PMCPMC10953702
OpenAlexW4389196051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.