Evidence map›Paper›PMID 38035366›Full record

ArticleBrain communications2023

Congenital myasthenic syndromes: a retrospective natural history study of respiratory outcomes in a single centre.

Jordan Poulos, Martin Samuels, Jacqueline Palace, David Beeson, Stephanie Robb, Sithara Ramdas, Samantha Chan, Pinki Munot

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jordan PoulosPaediatrics, University College London Medical School, London WC1E 6BT, UK.
Martin SamuelsRespiratory Medicine, Great Ormond Street Hospital, London WC1N 3JH, UK.ORCID https://orcid.org/0000-0002-9811-8335
Jacqueline PalaceUniversity of Oxford and Department of Neurology, Oxford Radcliffe Hospitals, Oxford OX3 9DU, UK.
David BeesonNeurology, Nuffield Department of Clinical Neurosciences, Oxford OX3 7BN, UK.ORCID https://orcid.org/0000-0001-9395-7132
Stephanie RobbDubowitz Neuromuscular Centre, Great Ormond Street Hospital, London WC1N 3JH, UK.
Sithara RamdasNeurology, MDUK Neuromuscular Centre, Oxford University Hospitals, Oxford OX3 9DU, UK.ORCID https://orcid.org/0000-0003-3790-2190
Samantha ChanDubowitz Neuromuscular Centre, Great Ormond Street Hospital, London WC1N 3JH, UK.ORCID https://orcid.org/0000-0003-0488-1207
Pinki MunotDubowitz Neuromuscular Centre, Great Ormond Street Hospital, London WC1N 3JH, UK.ORCID https://orcid.org/0000-0001-9900-798X
Great Ormond Street Hospital · GBOxford University Hospitals NHS Trust · GBUniversity College London · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory problems are a major cause of morbidity and mortality in patients with congenital myasthenic syndromes, a rare heterogeneous group of neuromuscular disorders caused by genetic defects impacting the structure and function of the neuromuscular junction. Recurrent, life-threatening episodic apnoea in early infancy and childhood and progressive respiratory failure requiring ventilation are features of certain genotypes of congenital myasthenic syndromes. Robb

Indexed as

congenital myasthenic syndromesrespiratorysleep studyspirometry

Identifiers

PMID38035366
PMCPMC10684295
OpenAlexW4388590004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.