Evidence map›Paper›PMID 38035258›Full record

ArticleInternational journal of cardiology. Heart & vasculature2023

Amir Samii, Saeed Aslani, Danyal Imani, Bahman Razi, Seyedeh Samaneh Tabaee, Tannaz Jamialahmadi, Amirhossein Sahebkar

Abstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Observational
  5. Association ofGenes · 2025
    Article
  6. Children (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Article
  9. Impact ofReports of biochemistry & molecular biology · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amir SamiiDepartment of Hematology and Blood Transfusion, School of Allied Medical Science, Iran University of Medical Sciences, Tehran, Iran.
Saeed AslaniDepartment of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Danyal ImaniDepartment of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Bahman RaziDepartment of Hematology and Blood Transfusion, Faculty of Medical Sciences, Tarbiat Modares University (TMU), Tehran, Iran.
Seyedeh Samaneh TabaeeNoncommunicable Disease Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Tannaz JamialahmadiInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Amirhossein SahebkarBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This meta-analysis aimed to provide a comprehensive assessment of the association between Methylenetetrahydrofolate reductase ( Methods: A systematic literature search was conducted in MEDLINE, Web of Science, and Scopus until April 2023 to identify studies investigating the relationship between Results: The analysis included 66 studies involving 16,860 cases and 20,403 controls for the C677T polymorphism and 18 studies comprising 3162 cases and 3632 controls for the A1298C polymorphism. Significant associations were observed between the C677T polymorphism and MI risk in various genetic models: dominant (OR = 1.16, 95 % CI = 1.06-1.28, Conclusions: This meta-analysis revealed an association between

Indexed as

Genetic polymorphismHeterogeneityMeta-analysisMethylenetetrahydrofolate reductaseMIMyocardial infarction

Identifiers

PMID38035258
PMCPMC10687297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.