Evidence map›Paper›PMID 38035205›Full record

ArticleCurrent developments in nutrition2023

Opportunities for Examining Child Health Impacts of Early-Life Nutrition in the ECHO Program: Maternal and Child Dietary Intake Data from Pregnancy to Adolescence.

Megan G Bragg, Matt Westlake, Akram N Alshawabkeh, Traci A Bekelman, Carlos A Camargo, Diane J Catellier, Sarah S Comstock, Dana Dabelea, Anne L Dunlop, Monique M Hedderson and 23 more

Open access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Article
  3. Methodological challenges and opportunities when studying the course of autism.Autism : the international journal of research and practice · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 18 institutions in 1 country.

Megan G BraggAJ Drexel Autism Institute, Drexel University, Philadelphia, PA, United States.
Matt WestlakeRTI International, Research Triangle Park, NC, United States.
Akram N AlshawabkehCollege of Engineering, Northeastern University, Boston, MA, United States.
Traci A BekelmanLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Carlos A CamargoMassachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Diane J CatellierRTI International, Research Triangle Park, NC, United States.
Sarah S ComstockDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Dana DabeleaLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Anne L DunlopDepartment of Gynecology & Obstetrics, Emory University School of Medicine, Atlanta, GA, United States.
Monique M HeddersonKaiser Permanente Northern California Division of Research, Oakland, CA, United States.
Christine W HockettAvera Research Institute, Sioux Falls, SD, United States.
Margaret R KaragasDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, United States.
Kate KeenanDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, Chicago, IL, United States.
Nichole R KellyDepartment of Counseling Psychology and Human Services, College of Education, University of Oregon, Eugene, OR, United States.
Jean M KerverDepartments of Epidemiology & Biostatistics and Pediatrics & Human Development, College of Human Medicine, Michigan State University, East Lansing, MI, United States.
Debra MacKenzieCommunity Environmental Health Program, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, NM, United States.
Somdat MahabirNational Cancer Institute, National Institutes of Health, Bethesda, MD, United States.
Luis E MaldonadoDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Lacey A McCormackAvera Research Institute, Sioux Falls, SD, United States.
Melissa M MeloughDepartment of Health Behavior and Nutrition Sciences, University of Delaware, Newark, DE, United States.
Noel T MuellerDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Morgan E NelsonRTI International, Research Triangle Park, NC, United States.
Thomas G O'ConnorDepartments of Psychiatry, Neuroscience, Obstetrics and Gynecology, University of Rochester, Rochester, NY, United States.
Emily OkenDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, United States.
T Michael O'SheaDepartment of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
Karen M SwitkowskiDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, United States.
Katherine A SauderLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Rosalind J WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Robert O WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Xueying ZhangDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Yeyi ZhuKaiser Permanente Northern California Division of Research, Oakland, CA, United States.
Kristen LyallAJ Drexel Autism Institute, Drexel University, Philadelphia, PA, United States.
program collaborators for Environmental influences on Child Health Outcomes
Harvard University · USIcahn School of Medicine at Mount Sinai · USRTI International · USUniversity of Colorado Anschutz Medical Campus · USDrexel University · USKaiser Permanente · USMichigan State University · USUniversity of South Dakota · USDartmouth College · USEmory University · USJohns Hopkins University · USNational Institutes of Health · USNortheastern University · USSeattle Children's Hospital · USUniversity of Chicago · USUniversity of New Mexico · USUniversity of Oregon · USUniversity of Southern California · US

Funding

Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUH3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern · 2018 to 2026
$64.8M
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
Environmental Influences on Childhood Outcomes in the Northern Plains Safe Passage Study CohortsUH3OD023279 · OD · AVERA MCKENNAN · PI Amy J Elliott, Christine W Hockett · 2018 to 2026
$31.7M
The Role of the Placenta-Brain Axis in Children's NeurodevelopmentUH3OD023348 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Rebecca Fry, Michael O'SHEA · 2018 to 2026
$21.9M
Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUG3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI GERN, JAMES E. · 2016 to 2024
$19.3M
Environmental Influences on Child Health Outcomes in the Northern Plains Safe Passage Study CohortUG3OD023279 · OD · SANFORD RESEARCH/USD · PI ELLIOTT, AMY J, HOCKETT, CHRISTINE W · 2016 to 2024
$17.5M
Understanding Risk Gradients from Environment on Native American Child Health Trajectories: Toxicants, Immunomodulation, Metabolic syndromes, & Metals ExposureUG3OD023344 · OD · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LEWIS, JOHNNYE L, MACKENZIE, DEBRA · 2016 to 2024
$14.1M
Early Life Exposure to Endocrine Disrupting Chemicals and Child Growth, Adiposity, and NeurodevelopmentUG3OD023289 · OD · KAISER FOUNDATION RESEARCH INSTITUTE · PI CROEN, LISA A, FERRARA, ASSIAMIRA · 2016 to 2024
$9.8M
Environment, Epigenetics, Neurodevelopment & Health of Extremely Preterm ChildrenUG3OD023348 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRY, REBECCA, O'SHEA, MICHAEL · 2016 to 2024
$7.4M
Preconception and Prenatal Health Impacting Factors and Child HealthUG3OD035540 · OD · KAISER FOUNDATION RESEARCH INSTITUTE · PI AVALOS, LYNDSAY AMMON, HEDDERSON, MONIQUE MARIE · 2023 to 2024
$6.4M
ECHO Renewal for the INSPIRE Study CohortUG3OD035516 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BACHARIER, LEONARD B, HARTERT, TINA V · 2023 to 2024
$3.5M
Childhood Allergy and the NeOnatal Environment (CANOE) ECHO Pediatric Follow-Up and New EnrollmentUH3OD035509 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Anne Marie Singh · 2025 to 2026
$3.1M
NCATS NIH HHS UL1 TR004419NIH HHS UG3 OD023279NIH HHS UG3 OD023282NIH HHS UG3 OD023289NIH HHS UG3 OD023344NIH HHS UG3 OD023348NIH HHS UG3 OD035509NIH HHS UG3 OD035516NIH HHS UG3 OD035517NIH HHS UG3 OD035540NIH HHS UH3 OD023279NIH HHS UH3 OD023282NIH HHS UH3 OD023348NIH HHS UH3 OD035509
6 · The paper itself

Abstract

Background: Longitudinal measures of diet spanning pregnancy through adolescence are needed from a large, diverse sample to advance research on the effect of early-life nutrition on child health. The Environmental influences on Child Health Outcomes (ECHO) Program, which includes 69 cohorts, >33,000 pregnancies, and >31,000 children in its first 7-y cycle, provides such data, now publicly available. Objectives: This study aimed to describe dietary intake data available in the ECHO Program as of 31 August, 2022 (end of year 6 of Cycle 1) from pregnancy through adolescence, including estimated sample sizes, and to highlight the potential for future analyses of nutrition and child health. Methods: We identified and categorized ECHO Program dietary intake data, by assessment method, participant (pregnant person or child), and life stage of data collection. We calculated the number of maternal-child dyads with dietary data and the number of participants with repeated measures. We identified diet-related variables derived from raw dietary intake data and nutrient biomarkers measured from biospecimens. Results: Overall, 66 cohorts (26,941 pregnancies, 27,103 children, including 22,712 dyads) across 34 US states/territories provided dietary intake data. Dietary intake assessments included 24-h recalls (1548 pregnancies and 1457 children), food frequency questionnaires (4902 and 4117), dietary screeners (8816 and 23,626), and dietary supplement use questionnaires (24,798 and 26,513). Repeated measures were available for ∼70%, ∼30%, and ∼15% of participants with 24-h recalls, food frequency questionnaires, and dietary screeners, respectively. The available diet-related variables describe nutrient and food intake, diet patterns, and breastfeeding practices. Overall, 17% of participants with dietary intake data had measured nutrient biomarkers. Conclusions: ECHO cohorts have collected longitudinal dietary intake data spanning pregnancy through adolescence from a geographically, socioeconomically, and ethnically diverse US sample. As data collection continues in Cycle 2, these data present an opportunity to advance the field of nutrition and child health.

Indexed as

child healthchild nutritiondiet assessmentnutrient biomarkersnutrition researchpregnancy nutrition

Identifiers

PMID38035205
PMCPMC10681943
OpenAlexW4387881512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.