Evidence map›Paper›PMID 38035105›Full record

ArticleFrontiers in immunology2023

Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4

Simone Sandoval, Keegan Malany, Krista Thongphanh, Clarisa A Martinez, Michael L Goodson, Felipe Da Costa Souza, Lo-Wei Lin, Nicolle Sweeney, Jamie Pennington, Pamela J Lein and 2 more

Open access · goldAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Simone SandovalDepartment of Environmental Toxicology, College of Agriculture and Environmental Science, University of California, Davis, Davis, CA, United States.
Keegan MalanyDepartment of Environmental Toxicology, College of Agriculture and Environmental Science, University of California, Davis, Davis, CA, United States.
Krista ThongphanhDepartment of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Clarisa A MartinezDepartment of Environmental Toxicology, College of Agriculture and Environmental Science, University of California, Davis, Davis, CA, United States.
Michael L GoodsonDepartment of Environmental Toxicology, College of Agriculture and Environmental Science, University of California, Davis, Davis, CA, United States.
Felipe Da Costa SouzaDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Lo-Wei LinDepartment of Environmental Toxicology, College of Agriculture and Environmental Science, University of California, Davis, Davis, CA, United States.
Nicolle SweeneyDivision of Rheumatology, Allergy and Clinical Immunology, Department of Internal Medicine, University of California, Davis, Davis, CA, United States.
Jamie PenningtonDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, United States.
Pamela J LeinDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Nancy I KerkvlietDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, United States.
Allison K EhrlichDepartment of Environmental Toxicology, College of Agriculture and Environmental Science, University of California, Davis, Davis, CA, United States.
University of California, Davis · USOregon State University · US

Funding

UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Nicholas J. KENYON · 2015 to 2026
$26.0M
ENVIRONMENTAL TOXICOLOGYT32ES007059 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura S Van Winkle · 1985 to 2026
$7.9M
The AHR as a Novel Pathway to the Induction of Regulatory T cellsR01ES016651 · NIEHS · OREGON STATE UNIVERSITY · PI KERKVLIET, NANCY I · 2009 to 2017
$3.5M
AhR activation and susceptibility to type 1 diabetesR00DK117509 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI EHRLICH, ALLISON · 2020 to 2022
$747k
AhR activation and susceptibility to type 1 diabetesK99DK117509 · NIDDK · OREGON STATE UNIVERSITY · PI EHRLICH, ALLISON · 2017 to 2018
$182k
NIDDK NIH HHS K99 DK117509NIDDK NIH HHS R00 DK117509NIEHS NIH HHS P30 ES023513NIEHS NIH HHS R01 ES016651NIEHS NIH HHS T32 ES007059
6 · The paper itself

Abstract

Neuropilin-1 (Nrp1), a transmembrane protein expressed on CD4

Indexed as

Interleukin-2Neuropilin-1Receptors, Aryl HydrocarbonAnimalsBasic Helix-Loop-Helix ProteinsForkhead Transcription FactorsLigandsMiceMice, Inbred C57BLMice, Inbred NODT-Lymphocytes, RegulatoryUp-RegulationAhr protein, mouseBasic Helix-Loop-Helix ProteinsForkhead Transcription FactorsInterleukin-2LigandsNeuropilin-1Receptors, Aryl Hydrocarbonaryl hydrocarbon receptorCD4+ T cellsIL-2immunomodulatorsneuropilin-1

Identifiers

PMID38035105
PMCPMC10682649
OpenAlexW4388657300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.