Evidence map›Paper›PMID 38035035›Full record

ArticleEuropean heart journal open2023

Blood pressure control in hypertensive sleep apnoea patients of the European Sleep Apnea Database cohort - effects of positive airway pressure and antihypertensive medication.

Sven Svedmyr, Jan Hedner, Sebastien Bailly, Francesco Fanfulla, Holger Hein, Carolina Lombardi, Ondrej Ludka, Stefan Mihaicuta, Gianfranco Parati, Athanasia Pataka and 6 more

Open access · goldAbstract read
In one paragraph

Article in European heart journal open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Obstructive sleep apnea -related hypertension: a review of the literature and clinical management strategy.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 8 countries.

Sven SvedmyrDepartment of Sleep Medicine, Sahlgrenska University Hospital, Blå stråket 5, 413 45 Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-5786-7938
Jan HednerDepartment of Sleep Medicine, Sahlgrenska University Hospital, Blå stråket 5, 413 45 Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-7190-394X
Sebastien BaillyUniversité Grenoble Alpes, INSERM HP2 (U1042) and Grenoble University Hospital, Grenoble, France.
Francesco FanfullaUnità Operativa di Medicina del Sonno, Istituto Scientifico di Pavia IRCCS, Pavia, Italy.
Holger HeinSleep Disorders Center, St.Adolf Stift, Reinbeck, Germany.
Carolina LombardiCardiology Unit, Sleep Center, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Ondrej LudkaDepartment of Internal Medicine, University Hospital Brno, Brno, Czech Republic.
Stefan MihaicutaCenter for Research and Innovation in Precision Medicine and Pharmacy, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Gianfranco ParatiCardiology Unit, Sleep Center, IRCCS Istituto Auxologico Italiano, Milan, Italy.ORCID https://orcid.org/0000-0001-9402-7439
Athanasia PatakaRespiratory Failure Unit, G. Papanikolaou Hospital, Aristotle University of Thessalonikii, Thessalonikii, Greece.ORCID https://orcid.org/0000-0002-3252-6694
Sophia SchizaSleep Disorders Unit, Department of Respiratory Medicine, School of Medicine, University of Crete, Crete, Greece.
Sezai TasbakanDepartment of Chest Diseases, Ege University, Izmir, Turkey.ORCID https://orcid.org/0000-0003-4507-9851
Dries TestelmansSleep Disorders Centre, University Hospital Gasthuisberg, Leuven, Belgium.ORCID https://orcid.org/0000-0001-7303-9799
Ding ZouDepartment of Sleep Medicine, Sahlgrenska University Hospital, Blå stråket 5, 413 45 Gothenburg, Sweden.ORCID https://orcid.org/0000-0003-2057-8558
Ludger GroteDepartment of Sleep Medicine, Sahlgrenska University Hospital, Blå stråket 5, 413 45 Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-7405-1682
European Sleep Apnea Database (ESADA) study group
Sahlgrenska University Hospital · SEUniversity Hospital Brno · CZIRCCS Istituto Auxologico Italiano · ITEge University · TRUniversity of Pavia · ITAristotle University of Thessaloniki · GRKrankenhaus Reinbek - Startseite · DEUniversity of Crete · GRVictor Babeș University of Medicine and Pharmacy Timișoara · ROInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: We analysed longitudinal blood pressure (BP) data from hypertensive obstructive sleep apnoea (OSA) patients in the European Sleep Apnea Database cohort. The study investigated the interaction between positive airway pressure (PAP)-induced BP change and antihypertensive treatment (AHT). Methods and results: Hypertensive patients with AHT [monotherapy/dual therapy Conclusion: In this pan-European OSA patient cohort, BP control improved following initiation of PAP. Longer PAP treatment duration, was associated with a favourable effect on BP. Our study suggests that ACEI/ARB, alone or in combination with other drug classes, provides a particularly strong reduction of BP and better BP control when combined with PAP in OSA.

Indexed as

Antihypertensive treatmentESADAHypertensionObstructive sleep apnoeaPrecision medicine

Identifiers

PMID38035035
PMCPMC10686603
OpenAlexW4387701117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.