Evidence map›Paper›PMID 38034802›Full record

ArticleHeliyon2023

Cross-reactivity between

Negar Asgari, Ezzat Allah Ghaemi, Mohammad Hasan Naeimi, Alireza Tahamtan, Leonardo Antonio Sechi, Samin Zamani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Negar AsgariNeuroscience Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Ezzat Allah GhaemiDepartment of Microbiology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Mohammad Hasan NaeimiDepartment of Neurology, Sayyad Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
Alireza TahamtanDepartment of Microbiology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Leonardo Antonio SechiAzienda Ospedaliera Universitaria, Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43b, 07100, Sassari, Italy.
Samin ZamaniNeuroscience Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Golestan University of Medical Sciences · IRAzienda Ospedaliero Universitaria di Sassari · ITGolestan University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The etiology of Multiple sclerosis (MS) is complicated and can be affected by several environmental factors, such as Materials and methods: This case-control study examined 200 blood samples (100 MS patients and 100 HCs) to search for the MAP-specific IS900 gene. In addition, ELISA was conducted to determine the humoral response against MAP_4027 Results: The frequency of MAP detection based on the molecular method in MS patients and HCs was 48 % and 13 %, respectively ( Conclusion: Our research revealed a significant association between MAP and MS, highlighting the possible role of MAP as an important infection trigger factor of MS. It is hypothesized that cross-reactivity between MAP4027 and IRF5 may dysregulate immune homeostasis.

Indexed as

ELISAHumanInterferon regulatory factor 5 proteinMultiple sclerosisMycobacterium avium subspecies paratuberculosisNested PCR

Identifiers

PMID38034802
PMCPMC10686849
OpenAlexW4388802308

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.