Evidence map›Paper›PMID 38034452›Full record

Trial reportJPGN reports2023

Pilot Study of Ondansetron in Improvement of Pediatric Colonoscopy Preparation Outcomes at an Urban Academic Center.

Dalia Arostegui, Paige Armaly, Kenny Castro Ochoa, Vivian Vega Lemus, Juveria Peshimam, Shagun Sharma, Steven Schwarz, Thomas Wallach

Registry-linked trialOpen access · hybridAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in JPGN reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05439772 (Examining the Effect of Ondansetron on Bowel Prep Success), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05439772 phase4completednot on this map

Examining the Effect of Ondansetron on Bowel Prep Success

TypeinterventionalSponsorState University of New York - Downstate Medical CenterRan2021 to 2023Enrolled41ConditionsAbdominal Pain, Inflammatory Bowel Diseases, Eosinophilic Gastroenteritis, DiarrheaArmsOndansetron
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Dalia ArosteguiFrom the Division of Pediatric Gastroenterology, Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY.
Paige ArmalyDepartment of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY.
Kenny Castro OchoaFrom the Division of Pediatric Gastroenterology, Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY.
Vivian Vega LemusFrom the Division of Pediatric Gastroenterology, Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY.
Juveria PeshimamDepartment of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY.
Shagun SharmaFrom the Division of Pediatric Gastroenterology, Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY.
Steven SchwarzFrom the Division of Pediatric Gastroenterology, Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY.
Thomas WallachFrom the Division of Pediatric Gastroenterology, Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY.
SUNY Downstate Health Sciences University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To gather initial data on the effectiveness and tolerability of the addition of Ondansetron to bowel preparation regimens to justify a funded, larger, placebo-controlled study. Methods: Results: No benefit to BBPS from the addition of Ondansetron to bowel preparation was observed. Statistically significant improvement in reports of abdominal pain (35% decrease in Ondansetron arm) was noted with a Conclusion: No benefit to efficacy of preparation as measured by the BBPS was observed. A single dose of Ondansetron before bowel preparation reduced reports of abdominal pain by 35%, with other symptomatic improvements suggesting possible improvements to be confirmed by a higher-powered study. Trial registration: NCT05439772.

Indexed as

colonoscopyOndansetronpreparation

Identifiers

PMID38034452
PMCPMC10684247
OpenAlexW4386536893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.