Evidence map›Paper›PMID 38033986›Full record

ArticleOpen forum infectious diseases2023

Human Immunodeficiency Virus (HIV) Treatment With Antiretroviral Therapy Mitigates the High Risk of Mental Health Disorders Associated With HIV Infection in the US Population.

Djibril M Ba, Kathryn A Risher, Paddy Ssentongo, Yue Zhang, Qi Dai, Guodong Liu, Mamoudou Maiga, Xuehong Zhang, Brehima Diakite, Souleymane Dit Papa Coulibaly and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Djibril M BaDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Kathryn A RisherDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Paddy SsentongoDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-1565-5731
Yue ZhangDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Qi DaiDepartment of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Guodong LiuDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Mamoudou MaigaPreventive Medicine Department, Northwestern University, Chicago, Illinois, USA.
Xuehong ZhangDepartment of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Brehima DiakiteFaculty of Medicine and Odontostomatology, University of Sciences, Techniques, and Technologies of Bamako, Bamako, Mali.
Souleymane Dit Papa CoulibalyFaculty of Medicine and Odontostomatology, University of Sciences, Techniques, and Technologies of Bamako, Bamako, Mali.
Lifang HouPreventive Medicine Department, Northwestern University, Chicago, Illinois, USA.
Douglas L LeslieDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Vernon M ChinchilliDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Pennsylvania State University · USNorthwestern University · USUniversité des Sciences, des Techniques et des Technologies de Bamako · MLBrigham and Women's Hospital · USVanderbilt University · US

Funding

West Africa Self-Sampling HPV Based Cervical Cancer Control Program (WA-SS-HCCP) for WLWHA: Barriers, challenges, and needsU01CA275129 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JANE Louise HOLL, Lifang Hou · 2022 to 2026
$3.2M
NCI NIH HHS U01 CA275129
6 · The paper itself

Abstract

Background: Whether treatment of human immunodeficiency virus (HIV) with antiretroviral therapy (ART) is associated with lower risk of mental health disorders (MHDs) among people with HIV (PWH) remains unknown. We aim to determine the association between HIV and MHDs and whether ART alters the risk of MHDs among PWH in the US adult population. Methods: We conducted a real-world study using the Merative MarketScan claims database (2016-2020), identifying individuals with HIV (diagnosed using Results: A total of 313 539 individuals, with a mean age of 44.2 (standard deviation, 11.4) years, predominantly males (81.2%), residing in the South region of the US (50.9%) were included in the present analysis. During 671 880 person-years of follow-up, 46 235 incident MHD cases occurred. In the multivariable Cox proportional hazard model, living with HIV was associated with higher risk of incident MHDs. Relative to those without HIV, the adjusted hazard ratio was 1.85 (95% confidence interval [CI], 1.79-1.92; Conclusions: HIV was associated with an increased risk of developing MHDs. However, HIV treatment mitigated the risk.

Indexed as

ARTHIVmental healthreal-world dataUS

Identifiers

PMID38033986
PMCPMC10686352
OpenAlexW4388516039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.