Evidence map›Paper›PMID 38033776›Full record

ArticleFrontiers in neurology2023

Hyperemia in head injury: can transcranial doppler help to personalize therapies for intracranial hypertension?

Camilla Gelormini, Eleonora Ioannoni, Angela Scavone, Luca Pisapia, Francesco Signorelli, Nicola Montano, Marco Piastra, Anselmo Caricato

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Camilla GelorminiNeurointensive Care Unit, Department of Anesthesiology, Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Eleonora IoannoniNeurointensive Care Unit, Department of Anesthesiology, Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Angela ScavoneNeurointensive Care Unit, Department of Anesthesiology, Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Luca PisapiaNeurointensive Care Unit, Department of Anesthesiology, Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Francesco SignorelliNeurosurgery Section, Department of Neuroscience, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Nicola MontanoNeurosurgery Section, Department of Neuroscience, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Marco PiastraPediatric ICU and Trauma Center, Department of Anesthesiology, Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Anselmo CaricatoNeurointensive Care Unit, Department of Anesthesiology, Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: An increase in cerebral blood flow is frequent after traumatic brain injury (TBI) and can lead to brain swelling and refractory intracranial hypertension. We hypothesized that Transcranial EcoDoppler (TCD) monitoring could be useful to detect the cause of intracranial hypertension in these patients. Our main objective was to investigate if the increase of velocity in the middle cerebral artery (MCA) on TCD could be associated with intracranial hypertension. Methods: We retrospectively studied TBI patients consecutively monitored with TCD. Hyperemia was defined as MCA mean velocity higher than 80 cm/s. Intracranial hypertension was considered when hyperosmolar therapy, hyperventilation, or deep sedation was used. Results: We found hyperemia in 40 patients out of 118 (33.9%). On average, it started at day 2.1 ± 0.9 from admission and significantly increased (MCA velocity at day 1: 74 ± 25 cm/s vs. 109 ± 36 cm/s at day 4; Discussion: Hyperemia was frequent in our population of TBI patients and preceded intracranial hypertension. TCD monitoring, if performed on a daily regular basis, can be a useful method to detect this phenomenon and to guide the therapy. It could be a tool for a cause-oriented therapy of intracranial hypertension.

Indexed as

cerebral autoregulationcerebral hyperemiaintracranial hypertensiontranscranial dopplertraumatic brain injury

Identifiers

PMID38033776
PMCPMC10686491
OpenAlexW4388693149

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.