Evidence map›Paper›PMID 38033663›Full record

ArticleEvolutionary bioinformatics online2023

Multi-omics Analysis of Prognostic Significance and Immune Infiltration of FASTK Family Members in Kidney Renal Clear Cell Carcinoma.

Guanghui Zhong, Dali Wu, Haiping Chen, Lingfei Yan, Qi Xiang, Yufeng Liu, Tao Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evolutionary bioinformatics online, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Guanghui ZhongDepartment of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, China.
Dali WuDepartment of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, China.
Haiping ChenDepartment of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, China.
Lingfei YanDepartment of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, China.
Qi XiangDepartment of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, China.
Yufeng LiuDepartment of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, China.
Tao WangDepartment of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-8690-6097
Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The Fas-activated serine/threonine kinase (FASTK) family of proteins has been recently found to be able to regulate mitochondrial gene expression post-transcriptionally. Nonetheless, there is a paucity of study about the role of the FASTK family in kidney renal clear cell carcinoma (KIRC). This study was conducted to explore the correlation of FASTK family genes with expression, prognosis, and immune infiltration in KIRC. Methods: We collected the data from the UALCAN, GeneMANIA, STRING, CancerSEA, cBioPortal, Kaplan-Meier plotter, GEPIA, TISIDB and TIMER databases to evaluate the genetic alterations, differential expression, prognostic significance, and immune cell infiltration of FASTKs in patients with KIRC. Results: In tumor tissues of KIRC, the mRNA expression level of FASTK and TBRG4 was elevated, whereas that of FASTKD1, FASTKD2, and FASTKD5 was lowered compared with normal tissues ( Conclusions: Our research provided fresh insight and in-depth analysis to the selection of prognostic biological markers of FASTK family members in KIRC.

Indexed as

biomarkerFASTK familykidney renal clear cell carcinomaMulti-omics analysisprognosis

Identifiers

PMID38033663
PMCPMC10683404
OpenAlexW4389103384

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.