ArticlePLoS neglected tropical diseases2023
Large-scale releases and establishment of wMel Wolbachia in Aedes aegypti mosquitoes throughout the Cities of Bello, Medellín and Itagüí, Colombia.
Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Comparison of Oviposition and Adult Trapping to Monitor wMel Introgression for Wolbachia-Based Vector Control.The American journal of tropical medicine and hygiene · 2026Article
- Wolbachia prevalence in Aedes aegypti across five comunas of Medellín, Colombia: Implications for post-release surveillance.PLoS neglected tropical diseases · 2026Article
- Article
- The cost-effectiveness of Wolbachia-based biocontrol interventions for dengue: A scoping review of the available evidence.PLoS neglected tropical diseases · 2026Article
- Wolbachia introgression in Rio de Janeiro remains at sub-optimal levels 30 months after its decline: challenges in the sustainability of wMel interventions for dengue control.Memorias do Instituto Oswaldo Cruz · 2026Article
- LaboratoryFrontiers in cellular and infection microbiology · 2026Article
- Improving Wolbachia-based control programs in urban settings: Insights from spatial modeling.PLoS neglected tropical diseases · 2025Article
- Impact of larval diet on fitness outcomes of Aedes aegypti mosquitoes infected with wAlbB and wMelM.Parasites & vectors · 2025Article
- Heterogeneity in inhibition of genetically diverse dengue virus strains bybioRxiv : the preprint server for biology · 2025Article
- Spatio-temporal analysis of the distribution and co-circulation of dengue, chikungunya, and Zika in Medellín, Colombia, from 2013 to 2021.PLoS neglected tropical diseases · 2025Article
- Long-Term Durability and Public Health Impact of City-WideTropical medicine and infectious disease · 2025Article
- Meeting Report on an Integrated Research Agenda for Mosquito-Borne Arboviruses.Open forum infectious diseases · 2025Article
- The long-term persistence of the wMel strain in Rio de Janeiro is threatened by poor integrated vector management and bacterium fitness cost on Aedes aegypti.PLoS neglected tropical diseases · 2025Article
- Effect of Socioeconomic Strata and Land Cover on Dengue Hotspots in Medellin, Colombia.The American journal of tropical medicine and hygiene · 2025Article
- ExploitingPathogens (Basel, Switzerland) · 2025Review
- Correction: Large-scale releases and establishment of wMel Wolbachia in Aedes aegypti mosquitoes throughout the Cities of Bello, Medellín and Itagüí, Colombia.PLoS neglected tropical diseases · 2025Article
- Article
- Strain-specific quantification ofFrontiers in insect science · 2025Article
- Microbial gatekeepers: midgut bacteria inFrontiers in microbiology · 2025Review
- Wolbachia incompatible insect technique program optimization over large spatial scales using a process-based model of mosquito metapopulation dynamics.BMC biology · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
38 authors.
Funding
Abstract
backgroundThe wMel strain of Wolbachia has been successfully introduced into Aedes aegypti mosquitoes and has been shown to reduce the transmission of dengue and other Aedes-borne viruses. Here we report the entomological results from phased, large-scale releases of Wolbachia infected Ae. aegypti mosquitoes throughout three contiguous cities located in the Aburrá Valley, Colombia. METHODOLOGY/PRINCIPAL
findingsLocal wMel Wolbachia-infected Ae. aegypti mosquitoes were generated and then released in an initial release pilot area in 2015-2016, which resulted in the establishment of Wolbachia in the local mosquito populations. Subsequent large-scale releases, mainly involving vehicle-based releases of adult mosquitoes along publicly accessible roads and streets, were undertaken across 29 comunas throughout Bello, Medellín and Itagüí Colombia between 2017-2022. In 9 comunas these were supplemented by egg releases that were undertaken by staff or community members. By the most recent monitoring, Wolbachia was found to be stable and established at consistent levels in local mosquito populations (>60% prevalence) in the majority (67%) of areas.
conclusionThese results, from the largest contiguous releases of wMel Wolbachia mosquitoes to date, highlight the operational feasibility of implementing the method in large urban settings. Based on results from previous studies, we expect that Wolbachia establishment will be sustained long term. Ongoing monitoring will confirm Wolbachia persistence in local mosquito populations and track its establishment in the remaining areas.
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