Evidence map›Paper›PMID 38031967›Full record

ArticleGlobal spine journal2025

Alterations in Magnitude and Shape of Thoracic Kyphosis Following Surgical Correction for Adult Spinal Deformity.

Renaud Lafage, Junho Song, Bassel Diebo, Alan H Daniels, Peter G Passias, Christopher P Ames, Shay Bess, Robert Eastlack, Munish C Gupta, Richard Hostin and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global spine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 1 country.

Renaud LafageDepartment of Orthopaedic Surgery, Northwell Health, Lenox Hill Hospital, New York, NY, USA.ORCID 0000-0002-4820-1835
Junho SongIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Bassel DieboDepartment of Orthopaedic Surgery, Warren Alpert Medical School of Brown University, Providence, RI, USA.ORCID 0000-0002-7835-2263
Alan H DanielsDepartment of Orthopaedic Surgery, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Peter G PassiasNYU Langone Orthopedic Hospital, New York, NY, USA.
Christopher P AmesDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Shay BessDenver International Spine Center, Denver, CO, USA.
Robert EastlackScripps Clinic Medical Group, La Jolla, CA, USA.
Munish C GuptaDepartment of Orthopaedic Surgery, Washington University, St. Louis, MO, USA.ORCID 0000-0002-4711-4377
Richard HostinMedical City Spine Hospital, Dallas, TX, USA.
Khaled KebaishDepartment of Orthopaedic Surgery, Johns Hopkins Medical Center, Baltimore, MD, USA.ORCID 0000-0002-1235-6202
Han Jo KimHospital for Special Surgery, New York, NY, USA.
Eric KlinebergDepartment of Orthopaedic surgery, University of Texas Health, Houston, TX.
Gregory M MundisScripps Clinic Medical Group, La Jolla, CA, USA.
Justin S SmithDepartment of Neurosurgery, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0003-0467-5534
Christopher ShaffreyDuke University, Durham, NC, USA.
Frank SchwabDepartment of Orthopaedic Surgery, Northwell Health, Lenox Hill Hospital, New York, NY, USA.
Virginie LafageDepartment of Orthopaedic Surgery, Northwell Health, Lenox Hill Hospital, New York, NY, USA.ORCID 0000-0002-0119-7111
Douglas BurtonDepartment of Orthopedic Surgery and Sports Medicine, University of Kansas Medical Center, Kansas, KS, USA.
International Spine Study Group
Northwell Health · USBrown University · USScripps Clinic Medical Group · USDuke University · USHospital for Special Surgery · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins University · USMedical City Dallas Hospital · USNew York University Langone Orthopedic Hospital · USThe University of Texas Health Science Center at Houston · USTwin Cities Spine Center · USUniversity of California, San Francisco · USUniversity of Kansas Medical Center · USUniversity of Virginia · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective review of prospective multicenter data.

objectivesThis study aimed to investigate the shape of TK before and after fusion in ASD patients treated with long fusion.

methodsASD patients undergoing posterior spinal fusions including at least T5 to L1 without prior fusion extending to the thoracic spine were included. Patients were categorized based on the preoperative T1-T12 kyphosis into: Hypo-TK (if < 30°), Normal-TK, and Hyper-TK (if > 70°). Regional kyphosis at T10-L1 (Distal), T5-T10 (Middle), and T1-T5 (Proximal) and their relative contributions to total kyphosis were compared between groups, and the pre-to postoperative changes were investigated using paired

resultsIn total, 329 patients were included in this analysis (mean age: 57 ± 16 years, 79.6% female). Preoperative T1-T12 TK for the entire cohort was 40.9 ± 2° (32% Hypo-TK, 11% Hyper-TK, 57% Normal-TK). The Hypo-TK group had the smallest distal TK (5.9 vs 17.1 & 26.0), and middle TK (8.0 vs 25.3 & 45.4), but the percentage of contribution to total kyphosis was not significantly different (Distal: 24.1% vs 34.1% vs 32.8%; Middle: 46.6% vs 53.9% vs 56.8%, all

conclusionsPosterior spinal fusion for ASD alters the magnitude and shape of thoracic kyphosis. While 60% of patients had a normal TK at baseline, 30% of those patients developed iatrogenic hyperkyphosis postoperatively. Patients with baseline hypokyphosis were more likely to be corrected to normal TK than hyperkyphotic patients. Future research should investigate TK restoration in ASD and its impact on clinical outcomes and complications.

Indexed as

adult spinal deformityposterior spinal fusionproximal junctional kyphosisscoliosisthoracic kyphosis

Identifiers

PMID38031967
PMCPMC11877554
OpenAlexW4389179574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.