Evidence map›Paper›PMID 38031653›Full record

ReviewJournal of cellular and molecular medicine2024

Potential role of epithelial-mesenchymal transition induced by periodontal pathogens in oral cancer.

Yiwei Ma, Yingyi Yu, Yuqing Yin, Liu Wang, Huishun Yang, Shiyin Luo, Qifan Zheng, Yaping Pan, Dongmei Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Gut microbes · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. The Role ofCancers · 2025
    Review
  10. Cancers · 2025
    Review
  11. The Oral Microbiome and Cancer.Advances in experimental medicine and biology · 2025
    Review
  12. Review
  13. Article
  14. The Roles and Interactions ofPathogens (Basel, Switzerland) · 2024
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yiwei MaDepartment of Periodontics, School of Stomatology, China Medical University, Shenyang, China.ORCID 0000-0002-9536-2906
Yingyi YuDepartment of Periodontics, School of Stomatology, China Medical University, Shenyang, China.
Yuqing YinDepartment of Periodontics, School of Stomatology, China Medical University, Shenyang, China.
Liu WangDepartment of Periodontics, School of Stomatology, China Medical University, Shenyang, China.
Huishun YangDepartment of Periodontics, School of Stomatology, China Medical University, Shenyang, China.
Shiyin LuoDepartment of Periodontics, School of Stomatology, China Medical University, Shenyang, China.
Qifan ZhengDepartment of Periodontics, School of Stomatology, China Medical University, Shenyang, China.
Yaping PanDepartment of Periodontics and Oral Biology, School of Stomatology, China Medical University, Shenyang, China.
Dongmei ZhangDepartment of Periodontics and Oral Biology, School of Stomatology, China Medical University, Shenyang, China.
China Medical University · CN

Funding

National Natural Science Foundation of China NO.81970943
6 · The paper itself

Abstract

With the increasing incidence of oral cancer in the world, it has become a hotspot to explore the pathogenesis and prevention of oral cancer. It has been proved there is a strong link between periodontal pathogens and oral cancer. However, the specific molecular and cellular pathogenic mechanisms remain to be further elucidated. Emerging evidence suggests that periodontal pathogens-induced epithelial-mesenchymal transition (EMT) is closely related to the progression of oral cancer. Cells undergoing EMT showed increased motility, aggressiveness and stemness, which provide a pro-tumour environment and promote malignant metastasis of oral cancer. Plenty of studies proposed periodontal pathogens promote carcinogenesis via EMT. In the current review, we discussed the association between the development of oral cancer and periodontal pathogens, and summarized various mechanisms of EMT caused by periodontal pathogens, which are supposed to play an important role in oral cancer, to provide targets for future research in the fight against oral cancer.

Indexed as

Mouth NeoplasmsPorphyromonas gingivalisCarcinogenesisEpithelial-Mesenchymal TransitionFusobacterium nucleatumHumansepithelial-mesenchymal transitionFusobacterium nucleatumoral cancerperiodontal pathogensPorphyromonas gingivalis

Identifiers

PMID38031653
PMCPMC10805513
OpenAlexW4389180073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.