Evidence map›Paper›PMID 38031564›Full record

ArticleApplied intelligence (Dordrecht, Netherlands)2023

Multiscale Laplacian Learning.

Ekaterina Merkurjev, Duc Duy Nguyen, Guo-Wei Wei

Abstract read
In one paragraph

Article in Applied intelligence (Dordrecht, Netherlands), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ekaterina MerkurjevDepartment of Mathematics, Michigan State University, MI 48824, USA.
Duc Duy NguyenDepartment of Mathematics, University of Kentucky, KY 40506, USA.
Guo-Wei WeiDepartment of Mathematics, Department of Biochemistry and Molecular Biology, Department of Electrical and Computer Engineering Michigan State University, MI 48824, USA.

Funding

AI-based platform for predicting emerging vaccine-escape variants and designing mutation-proof antibodiesR01AI164266 · NIAID · UNIVERSITY OF GEORGIA · PI Guowei Wei, YONG-HUI ZHENG · 2022 to 2026
$2.7M
Synergistic integration of topology and machine learning for the predictions of protein-ligand binding affinities and mutation impactsR01GM126189 · NIGMS · MICHIGAN STATE UNIVERSITY · PI WEI, GUOWEI · 2018 to 2021
$1.4M
NIAID NIH HHS R01 AI164266NIGMS NIH HHS R01 GM126189
6 · The paper itself

Abstract

Machine learning has greatly influenced many fields, including science. However, despite of the tremendous accomplishments of machine learning, one of the key limitations of most existing machine learning approaches is their reliance on large labeled sets, and thus, data with limited labeled samples remains a challenge. Moreover, the performance of machine learning methods often severely hindered in case of diverse data, usually associated with smaller data sets or data associated with areas of study where the size of the data sets is constrained by high experimental cost and/or ethics. These challenges call for innovative strategies for dealing with these types of data. In this work, the aforementioned challenges are addressed by integrating graph-based frameworks, semi-supervised techniques, multiscale structures, and modified and adapted optimization procedures. This results in two innovative multiscale Laplacian learning (MLL) approaches for machine learning tasks, such as data classification, and for tackling data with limited samples, diverse data, and small data sets. The first approach, multikernel manifold learning (MML), integrates manifold learning with multikernel information and incorporates a warped kernel regularizer using multiscale graph Laplacians. The second approach, the multiscale MBO (MMBO) method, introduces multiscale Laplacians to the modification of the famous classical Merriman-Bence-Osher (MBO) scheme, and makes use of fast solvers. We demonstrate the performance of our algorithms experimentally on a variety of benchmark data sets, and compare them favorably to the state-of-art approaches.

Indexed as

graph-based methodsgraph Laplacianmanifold learningmultiscale framework

Identifiers

PMID38031564
PMCPMC10686291

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.