Evidence map›Paper›PMID 38031062›Full record

SynthesisEnvironmental health : a global access science source2023

Occupational exposure to respirable crystalline silica and lung cancer: a systematic review of cut-off points.

Julia Rey-Brandariz, Cristina Martínez, Cristina Candal-Pedreira, Mónica Pérez-Ríos, Leonor Varela-Lema, Alberto Ruano-Ravina

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Environmental health : a global access science source, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. High prevalence of respiratory diseases: a population-based ecological study, Sertão do Araripe, 2008-2019.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Julia Rey-BrandarizDepartment of Preventive Medicine and Public Health, Universidade de Santiago de Compostela, C/ San Francisco s/n, Santiago de Compostela, 15782, Spain.
Cristina MartínezAsturias Clinical Hospital, Oviedo, Spain.
Cristina Candal-PedreiraDepartment of Preventive Medicine and Public Health, Universidade de Santiago de Compostela, C/ San Francisco s/n, Santiago de Compostela, 15782, Spain.
Mónica Pérez-RíosDepartment of Preventive Medicine and Public Health, Universidade de Santiago de Compostela, C/ San Francisco s/n, Santiago de Compostela, 15782, Spain.
Leonor Varela-LemaDepartment of Preventive Medicine and Public Health, Universidade de Santiago de Compostela, C/ San Francisco s/n, Santiago de Compostela, 15782, Spain.
Alberto Ruano-RavinaDepartment of Preventive Medicine and Public Health, Universidade de Santiago de Compostela, C/ San Francisco s/n, Santiago de Compostela, 15782, Spain. alberto.ruano@usc.es.
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESUniversidade de Santiago de Compostela · ESHospital Universitario Central de Asturias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespirable crystalline silica (RCS) is associated with the development of lung cancer. However, there is uncertainty around the exposure threshold at which exposure to RCS may pose a clear risk for the development of lung cancer. The objective of this study was to review the cut-off points at which the risk of mortality or incidence of lung cancer due to occupational exposure to RCS becomes evident through a systematic review.

methodsWe conducted a search in PubMed, including cohort and case-control studies which assessed various categories of RCS exposure. A search was also conducted on the webpages of institutional organizations. A qualitative data synthesis was performed.

resultsTwenty studies were included. Studies that assessed lung cancer mortality and incidence displayed wide variability both in RCS exposure categories and related risks. Although most studies found no significant association for RCS exposure categories, it appears to be a low risk of lung cancer for mean concentrations of less than 0.07mg/m

conclusionsThere is a wide degree of heterogeneity in RCS exposure categories, with most studies observing no significant risk of lung cancer for the lowest exposure categories. Cut-off points differ between agencies but are nonetheless very similar and do not exceed 0.1mg/m

Indexed as

Air Pollutants, OccupationalLung NeoplasmsOccupational ExposureDustHumansInhalation ExposureSilicon DioxideAir Pollutants, OccupationalDustSilicon DioxideInternational agenciesLung cancerOccupational exposureRespirable crystalline silicaSystematic review

Identifiers

PMID38031062
PMCPMC10687911
OpenAlexW4389178844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.