Trial reportBMC geriatrics2023
Reducing fear and avoidance of memory loss improves mood and social engagement in community-based older adults: a randomized trial.
Trial report in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04821960 (Improving Emotional Well-being and Quality of Life in Older Adults Experiencing Dementia-related Fear.), which is not on this map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Emotional Well-being and Quality of Life in Older Adults Experiencing Dementia-related Fear.
Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- "Balanced Brain": development, implementation, and acceptability of an acceptance and commitment therapy-based pilot intervention to promote brain health in older veterans.Journal of behavioral medicine · 2026Article
- Self-Perceptions of Aging in Older Adults: A Network Analysis of Clinical and Non-Clinical Samples.Brain sciences · 2026Article
- Research on the intervention mechanism and dynamic evolution of the digital divide's impact on the physical and mental health of older adults: a system dynamics perspective.Frontiers in public health · 2026Article
- Heterogeneous frailty trajectories and their differential impact on social integration in older adults with COPD: a prospective longitudinal study.Frontiers in public health · 2026Article
- Chronic pain and subjective memory problems are dynamic risk factors for functional decline: An ACTIVE longitudinal study.Experimental gerontology · 2025Article
- Advancing Research on Fear of Dementia Through eHealth Solutions in an Aging Society.Alpha psychiatry · 2025Article
- Association of Alzheimer's disease concerns with amyloid burden and lifestyle behaviors in cognitively unimpaired older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Knowledge, Awareness, and Perceived Threat Toward Alzheimer's Disease Among the Family Caregivers of Individuals with Chronic Physical Conditions in Bangladesh.Journal of Alzheimer's disease reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 4 countries.
Funding
Abstract
backgroundAlzheimer's disease and related dementias (ADRD) are among the most feared age-related conditions. The aim of this study was to evaluate a brief psychological intervention to promote adaptive coping in older adults experiencing heightened fear of ADRD and investigate positive downstream effects on health-related secondary outcomes, including frequency of reported memory failures, psychosocial functioning, and quality of life.
methodsEighty-one older adults were recruited and randomized into REFRAME or active control intervention arms. Both groups received psycho-education and training in mindful monitoring of fears related to ADRD. The REFRAME group received an additional behavioral activation component intended to disrupt maladaptive avoidant coping (i.e., avoidance) strategies. Both groups completed 3-weeks of intervention exercises with accompanying questionnaires (baseline, mid- and post-intervention and 4-week follow-up).
resultsAdherence was strong (> 75%). We observed a significant reduction in ADRD-related fear and avoidance in both groups. Significant reductions were also observed for frequency of self-reported memory failures, anxiety, and depression. Depression was significantly reduced in the REFRAME group compared to the control group. Significant increases in participants' ability to participate in social activities and well-being were also observed.
conclusionsFindings suggest that a brief psychological intervention can mitigate ADRD-related fears and avoidant coping in older adults, and that benefits extend to broader health-related outcomes including anxiety, depression, social functioning, and well-being. Addressing ADRD-related fear has implications for healthy aging and risk reduction, as individuals may be more likely to engage in activities that are protective against ADRD but were previously avoided.
trial registrationhttps://clinicaltrials.gov/ct2/show/NCT04821960 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.