Evidence map›Paper›PMID 38030938›Full record

ArticleAAPS PharmSciTech2023

In Vitro and In Vivo Evaluation of Metformin Hydrochloride Hydrogels Developed with Experimental Design in the Treatment of Burns.

Emine Dilek Ozyilmaz, Rojhat Celikkaya, Tansel Comoglu, Hulda Rifat Ozakpinar, Kemal Behzatoglu

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in AAPS PharmSciTech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Emine Dilek OzyilmazDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Eastern Mediterranean University, North Cyprus via Mersin 10, Famagusta, 99628, Türkiye.ORCID http://orcid.org/0000-0002-1791-3055
Rojhat CelikkayaPlastic Surgery Clinic, Etlik City Hospital, Ankara, Türkiye.ORCID http://orcid.org/0009-0001-0651-6126
Tansel ComogluDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Ankara University, Ankara, Türkiye. comoglu@pharmacy.ankara.edu.tr.ORCID http://orcid.org/0000-0002-4221-5814
Hulda Rifat OzakpinarPlastic Surgery Clinic, Etlik City Hospital, Ankara, Türkiye.ORCID http://orcid.org/0000-0001-7071-367X
Kemal BehzatogluPathology Laboratory, Atakent Hospital, Acibadem University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0002-9843-9825
Ankara University · TRAcıbadem University Atakent Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burns alter the normal skin barrier and affect various host defense processes that help prevent infections. An ineffective repair process can lead to serious damage, such as the onset of an infection or skin loss, which can then harm the surrounding tissues and ultimately the entire organism. This study aims to prepare in situ gels containing metformin hydrochloride, a compound known for its wound healing properties. To achieve this, in situ gels were prepared using three different gelling agents (Poloxamer 407

Indexed as

BurnsMetforminAnimalsHydrogelsPoloxamerRatsRats, WistarResearch DesignHydrogelsMetforminPoloxamerburn wound healingexperimental designin situ gelin vivo testsmetformin hydrochloride

Identifiers

PMID38030938
OpenAlexW4389121262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.