Evidence map›Paper›PMID 38030862›Full record

ArticleInfection2024

Characterization of bla

Vincent F van Almsick, Annika Sobkowiak, Natalie Scherff, Franziska Schuler, Alexander Mellmann, Vera Schwierzeck

Open access · hybridAbstract read
In one paragraph

Article in Infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vincent F van AlmsickInstitute of Hygiene, University Hospital Münster, Robert-Koch-Straße 41, Münster, Germany. vincentfrederic.vanalmsick@ukmuenster.de.
Annika SobkowiakInstitute of Hygiene, University Hospital Münster, Robert-Koch-Straße 41, Münster, Germany.
Natalie ScherffInstitute of Hygiene, University Hospital Münster, Robert-Koch-Straße 41, Münster, Germany.
Franziska SchulerInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
Alexander MellmannInstitute of Hygiene, University Hospital Münster, Robert-Koch-Straße 41, Münster, Germany.
Vera SchwierzeckInstitute of Hygiene, University Hospital Münster, Robert-Koch-Straße 41, Münster, Germany.
University Hospital Münster · DE

Funding

Interdisziplinäres Zentrum für Klinische Forschung, Medizinische Fakultät, Universität Münster SEED/019/23
6 · The paper itself

Abstract

purposeCarbapenemase-producing Enterobacterales (CPE) pose a serious threat for healthcare facilities worldwide, yet the mode of transmission is often unclear. Recently, we recorded an increase of bla

methodsSamples were collected as part of clinical routine diagnostic or screening of multi-drug resistance bacteria (MDRB). Antimicrobial susceptibility testing was performed and all MDRB (n = 10) were sequenced by lrWGS for genotyping, identification of antimicrobial resistance (AMR) genes, and characterization of plasmids.

resultsWhile routine analysis of core genome multilocus sequence typing (cgMLST) did not show any genetic similarities between isolates, we found an unexpected high similarity in the plasmid diversity of different Enterobacterales in patients with previous medical treatment in the Ukraine. This included an IncL/M plasmid carrying bla

conclusionOur results show that lrWGS can be used in the routine setting to uncover similarities in plasmids and may give further information about potential epidemiologic associations. In the future, analysis of both AMR and non-AMR plasmids may provide an additional layer of information for molecular surveillance of CPE.

Indexed as

beta-LactamasesEscherichia coliAnti-Bacterial AgentsHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsMultilocus Sequence TypingPlasmidsAnti-Bacterial Agentsbeta-LactamasesAntimicrobial resistancebla OXA-48Long-read whole genome sequencingMulti-drug resistance bacteriaPlasmids

Identifiers

PMID38030862
PMCPMC10954994
OpenAlexW4389127008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.