Evidence map›Paper›PMID 38030667›Full record

ArticleScientific reports2023

Understanding the impact of acne vulgaris and associated psychological distress on self-esteem and quality of life via regression modeling with CADI, DLQI, and WHOQoL.

A S M Morshed, Towhida Noor, Md Ashraf Uddin Ahmed, Fahmida Sultana Mili, Shuma Ikram, Mashiqur Rahman, Shamim Ahmed, Mohammad Borhan Uddin

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07673094 (Comparison of Efficacy of Topical Clascoterone With Topical Adapalene in the Treatment of Mild Acne Vulgaris), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07673094 early_phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Efficacy of Topical Clascoterone With Topical Adapalene in the Treatment of Mild Acne Vulgaris

TypeinterventionalSponsorKhyber Teaching HospitalRan2026 to 2027Enrolled60ConditionsAcne VulgarisArmsClascoterone Cream 1%, Adapalene 0,1% cgel
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

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  14. Integrated COJournal of cosmetic dermatology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

A S M MorshedDepartment of Psychiatry, Dr. Sirajul Islam Medical College, Dhaka, Bangladesh.
Towhida NoorDepartment of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Md Ashraf Uddin AhmedDepartment of Medicine, BIRDEM General Hospital, Shahbag, Dhaka, Bangladesh.
Fahmida Sultana MiliDepartment of Obstetrics and Gynecology, Munshiganj General Hospital, Munshiganj, Dhaka, Bangladesh.
Shuma IkramDepartment of Pediatrics, East West Medical College and Hospital, Dhaka, Bangladesh.
Mashiqur RahmanDepartment of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka, 1229, Bangladesh.
Shamim AhmedDepartment of Psychiatry, Bangladesh Psychiatric Care Limited, Dhanmondi, Dhaka, Bangladesh.
Mohammad Borhan UddinDepartment of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka, 1229, Bangladesh. mohammad.uddin@northsouth.edu.
North South University · BDBangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders · BDBangladesh Medical University · BDEast West University · BDWorld University of Bangladesh · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne vulgaris (AV) is a psychosomatic disorder and can negatively affect individuals, especially in terms of psychological well-being, self-esteem, and quality of life (QoL). The current study aimed to investigate the association between AV and psychological health, as well as the influence of acne and psychological distress in predicting patients' self-esteem and QoL. This cross-sectional study included 150 patients clinically diagnosed with AV. The severity of acne was measured using GAGS, and following that, patients were instructed to complete the following forms: DASS-21, RSES, CADI, DLQI, and WHOQoL. Female AV patients had significantly higher depression (p = 0.003, t = 3.025) and anxiety (p < 0.001, t = 3.683). Pearson's correlation analysis indicated a strong, positive, and significant correlation between having acne and experiencing depression (r = 0.630), anxiety (r = 0.661), and stress (r = 0.758) (p < 0.001). Multiple regression analysis suggested acne and associated psychological distress had a significant and negative impact on the patient's self-esteem and quality of life. This study highlights the multifaceted consequences of AV and the need to manage its psychological distress. It emphasizes the need for holistic patient care that addresses acne's physical and emotional aspects, with the ultimate goal of enhancing well-being and QoL.

Indexed as

Acne VulgarisPsychological DistressCross-Sectional StudiesFemaleHumansQuality of LifeSeverity of Illness Index

Identifiers

PMID38030667
PMCPMC10687248
OpenAlexW4389179392

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.