SynthesisBritish journal of anaesthesia2024
Apnoeic oxygenation during paediatric tracheal intubation: a systematic review and meta-analysis.
Synthesis in British journal of anaesthesia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- A core outcome set for airway management research.Anaesthesia · 2026Pooled it
- Respiratory support during endotracheal intubation to improve intubation success in neonates.The Cochrane database of systematic reviews · 2026Pooled it
- Lung Volume Change Under Apnoeic Oxygenation With Different Flow Rates in Children: A Single-Centre Prospective Randomized Controlled Non-Inferiority Trial.Paediatric anaesthesia · 2026Trial
- Non-Invasive respiratory support during elective intubation in preterm infants-a randomized controlled trial.BMC pediatrics · 2025Trial
- Current Use, Monitoring and Reversal of Neuromuscular Block in Pediatric Anesthesia and Intensive Care: A Web-Based Cross-Sectional ESAIC Survey.Paediatric anaesthesia · 2026Article
- Apneic time during intubation in critically ill children.Pediatric research · 2026Observational
- Preoxygenation in Infants: There's Only One Way to Do It, Right?Anesthesiology · 2026Article
- Effectiveness of Apneic Oxygenation During Induction of General Anesthesia in Children Undergoing Adenotonsillectomy: A Prospective Randomized Controlled Study.Anesthesiology and pain medicine · 2026Article
- Review
- All India Difficult Airway Association 2025 guidelines for the management of unanticipated difficult airway in paediatrics under general anaesthesia.Indian journal of anaesthesia · 2025Article
- The consensus statement of the Section of Paediatric Anaesthesiology and Intensive Therapy of the Polish Society of Anaesthesiology and Intensive Therapy on anaesthesia in children under 3 years of age.Anaesthesiology intensive therapy · 2025Article
- Article
- Apnoeic oxygenation in pediatric anesthesia: better safe than sorry!BMC anesthesiology · 2025Article
- Airway management in pediatrics: improving safety.Journal of anesthesia · 2025Review
- Attitudes of nursing professionals in adverse events in neonatal and pediatric intensive care.Revista da Escola de Enfermagem da U S P · 2025Article
- Endotracheal Intubation Outside the Operating Room: Year in Review 2023.Respiratory care · 2024Review
- [Airway management in neonates and infants : Recommendations according to the ESAIC/BJA guidelines].Die Anaesthesiologie · 2024Article
- [Stress factor reduction when securing the airway in preterm infants and neonates-Apneic oxygenation].Die Anaesthesiologie · 2024Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSupplemental oxygen administration by apnoeic oxygenation during laryngoscopy for tracheal intubation is intended to prolong safe apnoea time, reduce the risk of hypoxaemia, and increase the success rate of first-attempt tracheal intubation under general anaesthesia. This systematic review examined the efficacy and effectiveness of apnoeic oxygenation during tracheal intubation in children.
methodsThis systematic review and meta-analysis included randomised controlled trials and non-randomised studies in paediatric patients requiring tracheal intubation, evaluating apnoeic oxygenation by any method compared with patients without apnoeic oxygenation. Searched databases were MEDLINE, Embase, Cochrane Library, CINAHL, ClinicalTrials.gov, International Clinical Trials Registry Platform (ICTRP), Scopus, and Web of Science from inception to March 22, 2023. Data extraction and risk of bias assessment followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) recommendation.
resultsAfter initial selection of 40 708 articles, 15 studies summarising 9802 children were included (10 randomised controlled trials, four pre-post studies, one prospective observational study) published between 1988 and 2023. Eight randomised controlled trials were included for meta-analysis (n=1070 children; 803 from operating theatres, 267 from neonatal intensive care units). Apnoeic oxygenation increased intubation first-pass success with no physiological instability (risk ratio [RR] 1.27, 95% confidence interval [CI] 1.03-1.57, P=0.04, I
conclusionThis systematic review with meta-analysis confirms that apnoeic oxygenation during tracheal intubation of children significantly increases first-pass intubation success rate. Furthermore, apnoeic oxygenation enables stable physiological conditions by maintaining oxygen saturation within the normal range. CLINICAL
trial registrationProtocol registered prospectively on PROSPERO (registration number: CRD42022369000) on December 2, 2022.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.