Evidence map›Paper›PMID 38029238›Full record

ArticleFrontiers in cellular and infection microbiology2023

Multi-function screening of probiotics to improve oral health and evaluating their efficacy in a rat periodontitis model.

Qingqing Nie, Xuchun Wan, Hua Tao, Qianqian Yang, Xueyang Zhao, Haixia Liu, Jun Hu, Yanan Luo, Ting Shu, Ran Geng and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 26 citations in OpenAlex.

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  14. Effect ofJournal of dental research · 2025
    Article
  15. Impact of LiveMicroorganisms · 2025
    Article
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  18. Review
  19. Cyclodextran preventsFrontiers in oral health · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Qingqing Nie *Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Xuchun Wan *Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Hua Tao *Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Qianqian YangDepartment of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Xueyang ZhaoCollege of Life Sciences, Henan Normal University, Xinxiang, Henan, China.
Haixia LiuHuayuan Biotechnology Institute, Beijing, China.
Jun HuNational Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Yanan LuoDepartment of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Ting ShuDepartment of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Ran GengHuayuan Biotechnology Institute, Beijing, China.
Zhijing GuHuayuan Biotechnology Institute, Beijing, China.
Fengkai FanHubei Key Laboratory of Purification and Application of Plant Anti-Cancer Ingredients, College of Chemistry and Life Science, Hubei University of Education, Wuhan, China.
Zhi LiuDepartment of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Huazhong University of Science and Technology · CNHua Yuan Group (China) · CNChinese Academy of Sciences · CNHenan Normal University · CNHubei University of Education · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral cavity is the second most microbially rich region of the human body, and many studies have shown that there is a strong association between microorganisms and oral health. Some pathogenic bacteria produce biofilms and harmful metabolites in the mouth that may cause oral problems such as oral malodor, periodontitis, and dental caries. Altering the oral microbiota by using probiotics may alleviate oral health problems. Thus, using multi-function screening, we aimed to identify probiotics that can significantly improve oral health. The main parameters were the inhibition of pathogenic bacteria growth, inhibition of biofilm formation, reduction in the production of indole, H

Indexed as

Dental CariesHalitosisPeriodontitisProbioticsAnimalsCatsHumansHydrogen PeroxideIndolesMiceOral HealthRatsHydrogen PeroxideIndolesoral healthoral malodorperiodontitisprobioticstooth caries

Identifiers

PMID38029238
PMCPMC10660970
OpenAlexW4388459129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.