ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2023
Use of nares swab to de-escalate vancomycin for patients with suspected methicillin-resistant
Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Improving Empiric Antibiotic Selection for Patients Hospitalized With Skin and Soft Tissue Infection: The INSPIRE 3 Skin and Soft Tissue Randomized Clinical Trial.JAMA internal medicine · 2025Trial
- Nasal swab-guided deescalation of empirical linezolid in respiratory infections at a secondary-level hospital: quantification of quality gaps and antimicrobial stewardship opportunities.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026Observational
- A Quality Improvement Project to Increase Pharmacist-Initiated Methicillin ResistantThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Methicillin-ResistantOpen forum infectious diseases · 2026Review
- Retrospective Evaluation of Empiric Vancomycin Therapy for Infectious Workups in Relation to Methicillin-ResistantThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025Article
- Implementation of an automated methicillin-resistantAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Introduction: According to the US Center for Disease Control and Prevention, 30%-50% of antibiotic use in hospitals is unnecessary or inappropriate. The coronavirus disease 2019 pandemic further complicates antibiotic use leading to greater initiation of empiric antibiotics. The result is antibiotic overuse and increased duration of unnecessary therapy. Vancomycin is a drug of last resort, primarily relegated to the treatment of Methicillin-Resistant Methods: This before-and-after study examines the impact of vancomycin therapy de-escalation due to absence of MRSA colonization detected via PCR assay of nares swabs. An intervention with providers using SMART goals was designed to increase nasal swabbing for MRSA and ultimately decrease vancomycin use at a large, tertiary-care urban hospital. Results: There was a significant increase in use of vancomycin nares swabs (28/150 vs 48/100, Conclusion: An intervention using PCR nares swabs to detect MRSA led to significant, lasting decreases in vancomycin usage at this hospital. Similar interventions should be planned at hospitals experiencing overuse of this antibiotic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.